Abstract Purpose of Review Fibromyalgia Syndrome (FMS) is a complex chronic pain
condition characterized by widespread musculoskeletal pain and numerous other …

Positive allosteric modulators of γ-aminobutyric acid-A (GABA A) receptors, or GABAkines,
play important roles in the treatment of depression, epilepsy, insomnia, and other disorders …

Major depressive disorder (MDD) and postpartum depression (PPD) are common and
burdensome conditions. This study aims to evaluate the efficacy and safety of zuranolone, a …

Background Breathlessness frequently becomes severe among people with respiratory
disease. Mirtazapine, a widely used antidepressant, has shown promise in the modulation of …

Chronic pain has increasingly become a significant health challenge, not just as a
symptomatic manifestation but also as a pathological condition with profound …

Neuropathic pain is a challenging chronic pain condition. Limited knowledge exists
regarding the relative effectiveness of pharmacological treatments, and differences in trial …

One-fourth to one-third of women with endometriosis receiving first-line hormonal treatment
lacks an adequate response in terms of resolution of painful symptoms. This phenomenon …

Chronic musculoskeletal pain syndromes, including fibromyalgia, are often resistant to
conventional medications and invasive therapies. Central hypersensitization …

Pre-exposure prophylaxis (PrEP) is an effective biomedical strategy for HIV prevention. This
umbrella review is aimed at providing a comprehensive summary of the current status of …

Objective Post-stroke depression (PSD) is a prevalent and severe sequela of stroke. It is an
emotional disorder that significantly impacts functional recovery, prognosis, secondary …