Nociplastic pain is a mechanistic term used to describe pain that arises or is sustained by
altered nociception, despite the absence of tissue damage. Although nociplastic pain has …

Abstract Purpose of Review Fibromyalgia Syndrome (FMS) is a complex chronic pain
condition characterized by widespread musculoskeletal pain and numerous other …

Chronic pain has increasingly become a significant health challenge, not just as a
symptomatic manifestation but also as a pathological condition with profound …

Neuropathic pain is a challenging chronic pain condition. Limited knowledge exists
regarding the relative effectiveness of pharmacological treatments, and differences in trial …

Major depressive disorder (MDD) and postpartum depression (PPD) are common and
burdensome conditions. This study aims to evaluate the efficacy and safety of zuranolone, a …

Pre-exposure prophylaxis (PrEP) is an effective biomedical strategy for HIV prevention. This
umbrella review is aimed at providing a comprehensive summary of the current status of …

Positive allosteric modulators of γ-aminobutyric acid-A (GABA A) receptors, or GABAkines,
play important roles in the treatment of depression, epilepsy, insomnia, and other disorders …

Objective: This overview of systematic reviews (OoSRs) aimed, firstly, to systematically
review, summarize, and appraise the findings of published systematic reviews with or …

Objective The present study aimed to investigate the association between self-reported
awake/sleep bruxism, and orofacial pain with post-traumatic stress disorder (PTSD) …

Chronic musculoskeletal pain syndromes, including fibromyalgia, are often resistant to
conventional medications and invasive therapies. Central hypersensitization …