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Extending the “one strain many compounds”(OSMAC) principle to marine microorganisms
Genomic data often highlights an inconsistency between the number of gene clusters
identified using bioinformatic approaches as potentially producing secondary metabolites …
identified using bioinformatic approaches as potentially producing secondary metabolites …
Synthetic biology and metabolic engineering of actinomycetes for natural product discovery
Actinomycetes are one of the most valuable sources of natural products with industrial and
medicinal importance. After more than half a century of exploitation, it has become …
medicinal importance. After more than half a century of exploitation, it has become …
Reproducible molecular networking of untargeted mass spectrometry data using GNPS
Abstract Global Natural Product Social Molecular Networking (GNPS) is an interactive online
small molecule–focused tandem mass spectrometry (MS2) data curation and analysis …
small molecule–focused tandem mass spectrometry (MS2) data curation and analysis …
Natural product drug discovery in the genomic era: realities, conjectures, misconceptions, and opportunities
RH Baltz - Journal of Industrial Microbiology and Biotechnology, 2019 - academic.oup.com
Natural product discovery from microorganisms provided important sources for antibiotics,
anti-cancer agents, immune-modulators, anthelminthic agents, and insecticides during a …
anti-cancer agents, immune-modulators, anthelminthic agents, and insecticides during a …
Evolutionary dynamics of natural product biosynthesis in bacteria
Covering: 2008 up to 2019 The forces of biochemical adaptive evolution operate at the level
of genes, manifesting in complex phenotypes and the global biodiversity of proteins and …
of genes, manifesting in complex phenotypes and the global biodiversity of proteins and …
Antiproliferative and Antioxidative Bioactive Compounds in Extracts of Marine-Derived Endophytic Fungus Talaromyces purpureogenus
Endophytic fungi are now recognized as sources of pharmacologically beneficial, novel
bioactive compounds. This study was carried out to evaluate antiproliferative and …
bioactive compounds. This study was carried out to evaluate antiproliferative and …
[HTML][HTML] Recent Advances in Strategies for Activation and Discovery/Characterization of Cryptic Biosynthetic Gene Clusters in Streptomyces
Streptomyces spp. are prolific sources of valuable natural products (NPs) that are of great
interest in pharmaceutical industries such as antibiotics, anticancer chemotherapeutics …
interest in pharmaceutical industries such as antibiotics, anticancer chemotherapeutics …
Secondary metabolites released by the rhizosphere bacteria Arthrobacter oxydans and Kocuria rosea enhance plant availability and soil–plant transfer of germanium …
R Schwabe, C Dittrich, J Kadner, CHR Senges… - Chemosphere, 2021 - Elsevier
Here, we explore effects of metallophore-producing rhizobacteria on the plant availability of
germanium (Ge) and rare earth elements (REEs). Five isolates of the four species …
germanium (Ge) and rare earth elements (REEs). Five isolates of the four species …
Streptomyces Volatile Compounds Influence Exploration and Microbial Community Dynamics by Altering Iron Availability
SE Jones, CA Pham, MP Zambri, J McKillip… - MBio, 2019 - journals.asm.org
Bacteria and fungi produce a wide array of volatile organic compounds (VOCs), and these
can act as chemical cues or as competitive tools. Recent work has shown that the VOC …
can act as chemical cues or as competitive tools. Recent work has shown that the VOC …
A Streptomyces species from the ginseng rhizosphere exhibits biocontrol potential
J Huang, X Li, X Zhan, S Pan, C Pan, J Li… - Plant …, 2024 - academic.oup.com
Plants and their associated microbes live in complicated, changeable, and unpredictable
environments. They usually interact with each other in many ways through multidimensional …
environments. They usually interact with each other in many ways through multidimensional …