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Selective neuronal loss in ischemic stroke and cerebrovascular disease
JC Baron, H Yamauchi, M Fujioka… - Journal of Cerebral …, 2014 - journals.sagepub.com
As a sequel of brain ischemia, selective neuronal loss (SNL)—as opposed to pannecrosis
(ie infarction)—is attracting growing interest, particularly because it is now detectable in vivo …
(ie infarction)—is attracting growing interest, particularly because it is now detectable in vivo …
Bacteria hijack a meningeal neuroimmune axis to facilitate brain invasion
The meninges are densely innervated by nociceptive sensory neurons that mediate pain
and headache,. Bacterial meningitis causes life-threatening infections of the meninges and …
and headache,. Bacterial meningitis causes life-threatening infections of the meninges and …
Neuronal death after hemorrhagic stroke in vitro and in vivo shares features of ferroptosis and necroptosis
Background and Purpose—Intracerebral hemorrhage leads to disability or death with few
established treatments. Adverse outcomes after intracerebral hemorrhage result from …
established treatments. Adverse outcomes after intracerebral hemorrhage result from …
The impact of endothelial cell death in the brain and its role after stroke: a systematic review
The supply of oxygen and nutrients to the brain is vital for its function and requires a complex
vascular network that, when disturbed, results in profound neurological dysfunction. As part …
vascular network that, when disturbed, results in profound neurological dysfunction. As part …
Ischemia-selective cardioprotection by malonate for ischemia/reperfusion injury
Background: Inhibiting SDH (succinate dehydrogenase), with the competitive inhibitor
malonate, has shown promise in ameliorating ischemia/reperfusion injury. However, key for …
malonate, has shown promise in ameliorating ischemia/reperfusion injury. However, key for …
RTN1-C mediates cerebral ischemia/reperfusion injury via ER stress and mitochondria-associated apoptosis pathways
L Gong, Y Tang, R An, M Lin, L Chen, J Du - Cell death & disease, 2017 - nature.com
The reticulon family has been found to induce apoptosis, inhibit axon regeneration and
regulate protein trafficking. However, little is known about the mechanisms of how reticulon …
regulate protein trafficking. However, little is known about the mechanisms of how reticulon …
Potential anxiolytic and antidepressant-like effects of luteolin in a chronic constriction injury rat model of neuropathic pain: Role of oxidative stress, neurotrophins, and …
This study aimed to examine the effects of luteolin (LUT) on chronic neuropathic pain (NP)-
induced mood disorders (ie, anxiety and depression) by regulating oxidative stress …
induced mood disorders (ie, anxiety and depression) by regulating oxidative stress …
Exosomes from miRNA‐126‐modified endothelial progenitor cells alleviate brain injury and promote functional recovery after stroke
J Wang, S Chen, W Zhang, Y Chen… - CNS Neuroscience & …, 2020 - Wiley Online Library
Aims We previously showed that the protective effects of endothelial progenitor cells (EPCs)‐
released exosomes (EPC‐EXs) on endothelium in diabetes. However, whether EPC‐EXs …
released exosomes (EPC‐EXs) on endothelium in diabetes. However, whether EPC‐EXs …
Lactate dehydrogenase A mediated histone lactylation induced the pyroptosis through targeting HMGB1
X Yao, C Li - Metabolic Brain Disease, 2023 - Springer
Cerebral ischemia (CI), as the cerebrovascular disease with the highest incidence rate, is
treated by limited intravenous thrombolysis and intravascular therapy to recanalize the …
treated by limited intravenous thrombolysis and intravascular therapy to recanalize the …
The stroke preclinical assessment network: rationale, design, feasibility, and stage 1 results
Cerebral ischemia and reperfusion initiate cellular events in brain that lead to neurological
disability. Investigating these cellular events provides ample targets for develo** new …
disability. Investigating these cellular events provides ample targets for develo** new …