Zinc is a micronutrient of key importance for human health. An increasing number of studies
indicate that zinc plays a significant role in bone tissue's normal development and …

Hydroxyapatite is a basic mineral that is very important to the human body framework.
Recently, synthetic hydroxyapatite (SHA) and its nanocomposites (HANs) are the subject of …

Humans are exposed to nanoscopical nanobiovectors (eg coronavirus SARS-CoV-2) as
well as abiotic metal/carbon-based nanomaterials that enter cells serendipitously or …

Bone fractures and critical-size bone defects are significant public health issues, and clinical
treatment outcomes are closely related to the intrinsic properties of the utilized implant …

Zinc (Zn) is one of the most important trace elements in the human body and plays a key role
in various physiological processes, especially in bone metabolism. Zn-containing materials …

Polycaprolactone (PCL) is a polymer material suitable for being prepared into porous
scaffolds used in bone tissue engineering, however, insufficient osteogenic ability and …

Metal ions have been identified as important bone metabolism regulators and widely used in
the field of bone tissue engineering, however their exact role during bone regeneration …

The objective of the present study was to review recent epidemiological and clinical data on
the association between selected minerals and trace elements and osteoporosis, as well as …

Effective clinical methods for large bone defects are not yet available on account of the
complex intrinsic structure and mechanical characteristics of natural bone tissue. It remains …

Modern biomedicine aims to develop integrated solutions that use medical,
biotechnological, materials science, and engineering concepts to create functional …