Ca 2+ entry through the NMDA subtype of glutamate receptors has the power to determine
whether neurons survive or die. Too much NMDA receptor activity is harmful to neurons–but …

In the human brain and spinal cord, neurons degenerate after acute insults (eg, stroke,
cardiac arrest, trauma) and during progressive, adult-onset diseases [eg, amyotrophic lateral …

Young neurons born in the subventricular zone (SVZ) of adult mice migrate to the olfactory
bulb (OB) where they differentiate into granule cells (GCs) and periglomerular interneurons …

The cerebral cortex, occupying over 70 percent of our brain mass, is key to any
understanding of the workings--and disorders--of the human brain. offering a …

Plasticity in the brain reaches far beyond a mere changing of synaptic strengths. Recent time-
lapse imaging in the living brain reveals ongoing structural plasticity by forming or breaking …

The programmed cell death (PCD) of develo** cells is considered an essential adaptive
process that evolved to serve diverse roles. We review the putative adaptive functions of …

The role of adult hippocampal neurogenesis in spatial learning remains a matter of debate.
Here, we show that spatial learning modifies neurogenesis by inducing a cascade of events …

While larger brains possess concertedly larger cerebral cortices and cerebella, the relative
size of the cerebral cortex increases with brain size, but relative cerebellar size does not. In …

GABA, a major inhibitory neurotransmitter in the adult brain, activates synaptic and
extrasynaptic GABA A receptors, causing hyperpolarization of mature neurons. As in the …

▪ Abstract A growing family of genes that share homology with the bcl-2 proto-oncogene is
involved in the regulation of cell death. Many of these proteins show widespread expression …