Atherosclerosis is a chronic inflammatory disease, in which the immune system has a
prominent role in its development and progression. Inflammation-induced endothelial …

Dyslipidaemia has a prominent role in the onset of notorious atherosclerosis, a disease of
medium to large arteries. Atherosclerosis is the prime root of cardiovascular events …

Advanced atherosclerotic lesions contain senescent cells, but the role of these cells in
atherogenesis remains unclear. Using transgenic and pharmacological approaches to …

While risk scores are invaluable tools for adapted preventive strategies, a significant gap
exists between predicted and actual event rates. Additional tools to further stratify the risk of …

An ideal animal model of atherosclerosis resembles human anatomy and pathophysiology
and has the potential to be used in medical and pharmaceutical research to obtain results …

Atherosclerosis is a silent chronic vascular pathology that is the cause of the majority of
cardiovascular ischaemic events. The evolution of vascular disease involves a combination …

Current knowledge suggests that intimal smooth muscle cells (SMCs) in native
atherosclerotic plaque derive mainly from the medial arterial layer. During this process …

Recent years have brought a significant amount of new results in the field of atherosclerosis.
A better understanding of the role of different lipoprotein particles in the formation of …

Atherosclerosis is a chronic inflammatory disease of arteries and it affects the structure and
function of all three layers of the coronary artery wall. Current theories suggest that the …

Despite advances in our understanding of the pathophysiology of many cardiovascular
diseases (CVDs) and expansion of available therapies, the global burden of CVD …