Biomedical implants have been widely used in various orthopedic treatments, including total
hip arthroplasty, joint arthrodesis, fracture fixation, non-union, dental repair, etc. The modern …

Bone fractures are common occurrence in clinical settings, creating a high demand for
effective repair material. Unfortunately, limited graft availability, donor site morbidities …

Tough hydrogel has attracted considerable interest in various fields, however, due to poor
biocompatibility, nondegradation, and pronounced compositional differences from natural …

Interest in strontium (Sr) has persisted over the last three decades due to its unique
mechanism of action: it simultaneously promotes osteoblast function and inhibits osteoclast …

There is growing recognition of the role of micro-architecture in osteoporotic bone loss and
fragility. This trend has been driven by advances in imaging technology, which have …

Abstract Purpose of Review While thinning of the cortices or trabeculae weakens bone, age-
related changes in matrix composition also lower fracture resistance. This review …

Advances in vibrational spectroscopy have propelled new insights into the molecular
composition and structure of biological tissues. In this review, we discuss common …

Although musculoskeletal diseases such as osteoporosis are diagnosed and treatment
outcome is evaluated based mainly on routine clinical outcomes of bone mineral density …

As the application of Raman spectroscopy to study bone has grown over the past decade,
making it a peer technology to FTIR spectroscopy, it has become critical to understand their …

Synthetic substitutes of bone grafts, such as calcium phosphate–based ceramics, have
shown some good clinical successes in the regeneration of large bone defects and are …