Burnout and depression in nurses: a systematic review and meta-analysis

C Chen, ST Meier - International Journal of nursing studies, 2021‏ - Elsevier
Background Nurses work in stressful and demanding settings and often suffer from
depression and burnout. Despite overlap** symptoms, research has been inconclusive …

Stress, epigenetics and depression: a systematic review

C Park, JD Rosenblat, E Brietzke, Z Pan, Y Lee… - Neuroscience & …, 2019‏ - Elsevier
Environmental stressors, such as childhood maltreatment, have been recognized to
contribute to the development of depression. Growing evidence suggests that epigenetic …

The biology of burnout: Causes and consequences

A Bayes, G Tavella, G Parker - The World Journal of Biological …, 2021‏ - Taylor & Francis
Objectives Burnout is a state of exhaustion resulting from prolonged and excessive
workplace stress. We sought to examine biological underpinnings of burnout, focussing on …

Stress, burnout and depression: A systematic review on DNA methylation mechanisms

J Bakusic, W Schaufeli, S Claes, L Godderis - Journal of psychosomatic …, 2017‏ - Elsevier
Despite that burnout presents a serious burden for modern society, there are no diagnostic
criteria. Additional difficulty is the differential diagnosis with depression. Consequently, there …

The role of DNA methylation in stress-related psychiatric disorders

T Klengel, J Pape, EB Binder, D Mehta - Neuropharmacology, 2014‏ - Elsevier
Epigenetic modifications in response to traumatic experience and stress are emerging as
important factors in the long-term biological trajectories leading to stress-related psychiatric …

[HTML][HTML] The applied implications of epigenetics in anxiety, affective and stress-related disorders-A review and synthesis on psychosocial stress, psychotherapy and …

MA Schiele, MG Gottschalk, K Domschke - Clinical psychology review, 2020‏ - Elsevier
Mental disorders are highly complex and multifactorial in origin, comprising an elaborate
interplay of genetic and environmental factors. Epigenetic mechanisms such as DNA …

[PDF][PDF] Night shift work and risk of depression: meta-analysis of observational studies

A Lee, SK Myung, JJ Cho, YJ Jung… - Journal of Korean …, 2017‏ - synapse.koreamed.org
This study aimed to assess whether night shift work is associated with the risk of depression
by using a meta-analysis of observational studies. We searched PubMed and EMBASE in …

[HTML][HTML] Glucocorticoid signaling and epigenetic alterations in stress-related disorders

N Mourtzi, A Sertedaki, E Charmandari - International journal of molecular …, 2021‏ - mdpi.com
Stress is defined as a state of threatened or perceived as threatened homeostasis. The well-
tuned coordination of the stress response system is necessary for an organism to respond to …

Treatment-resistant depression revisited: a glimmer of hope

A Halaris, E Sohl, EA Whitham - Journal of personalized medicine, 2021‏ - mdpi.com
Major Depressive Disorder (MDD) is a highly prevalent psychiatric disorder worldwide. It
causes individual suffering, loss of productivity, increased health care costs and high suicide …

Epigenetic programming by stress and glucocorticoids along the human lifespan

AS Zannas, GP Chrousos - Molecular psychiatry, 2017‏ - nature.com
Psychosocial stress triggers a set of behavioral, neural, hormonal, and molecular responses
that can be a driving force for survival when adaptive and time-limited, but may also …