Multiple dysregulated signaling pathways are implicated in the pathogenesis of cancer. The
conventional therapies used in cancer prevention/treatment suffer from low efficacy …

Rutin is one of the most common dietary polyphenols found in vegetables, fruits, and other
plants. It is metabolized by the mammalian gut microbiota and absorbed from the intestines …

Cancer is a complex ailment orchestrated by numerous intrinsic and extrinsic pathways.
Recent research has displayed a deep interest in develo** plant-based cancer …

Several studies have documented the ability of flavonoids to sensitize cancer cells to
chemotherapeutics and reverse multidrug resistance by inhibition of efflux pumps …

Lung and colorectal cancer are the principal causes of death in the world. Rutin, an active
flavonoid compound, is known for possessing a wide range of biological activities. In this …

Microglia cells are the immune effector in the Central Nervous System (CNS). However,
studies have showed that they contribute more to glioma progression than to its elimination …

Fractionation of the chloroformic extracts from Teucrium ramosissimum leaves resulted in
the isolation of three flavonoids: genkwanin (1), cirsimaritin (2) and 4′, 7-dimethoxy …

High-grade adult-type diffuse gliomas are the most common and deadliest malignant adult
tumors of the central nervous system. Despite the advancements in the multimodality …

Glioma immunotherapy has attracted increasing attention since the immune system plays a
vital role in suppressing tumor growth. Immunotherapy strategies are already being tested in …

Bioavailability and biological properties of flavonoid glycosides can be improved after the
enzymatic hydrolysis of specific glycosyl groups. In this study, we evaluate the antioxidant …