[HTML][HTML] Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics

U Anand, A Dey, AKS Chandel, R Sanyal, A Mishra… - Genes & diseases, 2023 - Elsevier
Cancer is an abnormal state of cells where they undergo uncontrolled proliferation and
produce aggressive malignancies that causes millions of deaths every year. With the new …

Mechanism of antimicrobial peptides: antimicrobial, anti-inflammatory and antibiofilm activities

Y Luo, Y Song - International journal of molecular sciences, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are regarded as a new generation of antibiotics. Besides
antimicrobial activity, AMPs also have antibiofilm, immune-regulatory, and other activities …

Intratumoural administration and tumour tissue targeting of cancer immunotherapies

I Melero, E Castanon, M Alvarez, S Champiat… - Nature Reviews …, 2021 - nature.com
Immune-checkpoint inhibitors and chimeric antigen receptor (CAR) T cells are
revolutionizing oncology and haematology practice. With these and other immunotherapies …

Antimicrobial peptides towards clinical application: Delivery and formulation

C Wang, T Hong, P Cui, J Wang, J **a - Advanced drug delivery reviews, 2021 - Elsevier
Antimicrobial peptides hold promise to supplement small molecules antibiotics and combat
the multidrug resistant microbes. There are however technical hurdles towards the clinical …

[HTML][HTML] Immunomodulatory and allergenic properties of antimicrobial peptides

SV Guryanova, TV Ovchinnikova - International journal of molecular …, 2022 - mdpi.com
With the growing problem of the emergence of antibiotic-resistant bacteria, the search for
alternative ways to combat bacterial infections is extremely urgent. While analyzing the effect …

Nanotechnology-empowered strategies in treatment of skin cancer

J Chandra, N Hasan, N Nasir, S Wahab… - Environmental …, 2023 - Elsevier
In current scenario skin cancer is a serious condition that has a significant impact on world
health. Skin cancer is divided into two categories: melanoma skin cancer (MSC) and non …

Antimicrobial peptides and small molecules targeting the cell membrane of Staphylococcus aureus

N Ganesan, B Mishra, LO Felix… - … and Molecular Biology …, 2023 - journals.asm.org
Clinical management of Staphylococcus aureus infections presents a challenge due to the
high incidence, considerable virulence, and emergence of drug resistance mechanisms …

[HTML][HTML] From oncolytic peptides to oncolytic polymers: A new paradigm for oncotherapy

H Liu, W Shen, W Liu, Z Yang, D Yin, C **ao - Bioactive Materials, 2024 - Elsevier
Traditional cancer therapy methods, especially those directed against specific intracellular
targets or signaling pathways, are not powerful enough to overcome tumor heterogeneity …

Anti-cancer peptides: status and future prospects

G Ghaly, H Tallima, E Dabbish, N Badr ElDin… - Molecules, 2023 - mdpi.com
The dramatic rise in cancer incidence, alongside treatment deficiencies, has elevated
cancer to the second-leading cause of death globally. The increasing morbidity and mortality …

LL-37: structures, antimicrobial activity, and influence on amyloid-related diseases

S Bhattacharjya, Z Zhang, A Ramamoorthy - Biomolecules, 2024 - mdpi.com
Antimicrobial peptides (AMPs), as well as host defense peptides (HDPs), constitute the first
line of defense as part of the innate immune system. Humans are known to express …