Control of human viral infections by natural killer cells
S Jost, M Altfeld - Annual review of immunology, 2013 - annualreviews.org
Natural killer (NK) cells are effector cells of the innate immune system and are important in
the control of viral infections. Their relevance is reflected by the multiple mechanisms …
the control of viral infections. Their relevance is reflected by the multiple mechanisms …
Adaptive immune responses in acute and chronic hepatitis C virus infection
The hepatitis C virus (HCV) persists in the majority of infected individuals and is a significant
cause of human illness and death globally. Recent studies have yielded important insights …
cause of human illness and death globally. Recent studies have yielded important insights …
Changes in the global burden of chronic liver diseases from 2012 to 2017: the growing impact of NAFLD
Conclusions Our findings indicate that LINC00665 is involved in the NF‐κB signaling
activation in HCC cells and that the inflammatory LINC00665/PKR/NF‐κB loop plays …
activation in HCC cells and that the inflammatory LINC00665/PKR/NF‐κB loop plays …
CD39 Expression Identifies Terminally Exhausted CD8+ T Cells
Exhausted T cells express multiple co-inhibitory molecules that impair their function and limit
immunity to chronic viral infection. Defining novel markers of exhaustion is important both for …
immunity to chronic viral infection. Defining novel markers of exhaustion is important both for …
Broadly directed virus-specific CD4+ T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence
J Schulze zur Wiesch, D Ciuffreda… - Journal of Experimental …, 2012 - rupress.org
Vigorous proliferative CD4+ T cell responses are the hallmark of spontaneous clearance of
acute hepatitis C virus (HCV) infection, whereas comparable responses are absent in …
acute hepatitis C virus (HCV) infection, whereas comparable responses are absent in …
Peripheral CD4+CD8+ T cells are differentiated effector memory cells with antiviral functions
Although an increased frequency of CD4+ CD8+ T cells has been observed in the
peripheral blood during viral infections, their role, function, and biologic significance are still …
peripheral blood during viral infections, their role, function, and biologic significance are still …
[HTML][HTML] The role of Kupffer cells in hepatitis B and hepatitis C virus infections
Globally, over 500 million people are chronically infected with the hepatitis B virus (HBV) or
hepatitis C virus (HCV). These chronic infections cause liver inflammation, and may result in …
hepatitis C virus (HCV). These chronic infections cause liver inflammation, and may result in …
Flying under the radar: the immunobiology of hepatitis C
LB Dustin, CM Rice - Annu. Rev. Immunol., 2007 - annualreviews.org
The hepatitis C virus (HCV) is a remarkably successful pathogen, establishing persistent
infection in more than two-thirds of those who contract it. Its success is related to its abilities …
infection in more than two-thirds of those who contract it. Its success is related to its abilities …
Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers
Containment of hepatitis C virus (HCV) and other chronic human viral infections is
associated with persistence of virus-specific CD4 T cells, but ex vivo characterization of …
associated with persistence of virus-specific CD4 T cells, but ex vivo characterization of …
Elevated levels of IL-33, IL-17 and IL-25 indicate the progression from chronicity to hepatocellular carcinoma in hepatitis C virus patients
Hepatitis C virus (HCV) is one of the most epidemic viral infections in the world. Three-
quarters of individuals infected with HCV become chronic. As a consequence of persistent …
quarters of individuals infected with HCV become chronic. As a consequence of persistent …