An estimated 20% of all patients with cancer will develop brain metastases, with the majority
of brain metastases occurring in those with lung, breast and colorectal cancers, melanoma …

Brain, the major organ of the central nervous system controls and processes most of body
activities. Therefore, the most aggressive brain tumor–glioblastoma and metastases from …

Metastasis is the leading cause of cancer-related death, where TGFβ-induced epithelial-
mesenchymal transition (EMT) process confers on cancer cells increased metastatic …

Background Brain metastases are associated with significant morbidity and mortality.
Population-level data describing the incidence and prognosis of patients with brain …

Whole-brain radiotherapy (WBRT) is the treatment backbone for many patients with brain
metastasis; however, its efficacy in preventing disease progression and the associated …

In recent years, advances in melanoma treatment have renewed patient hope. This
comprehensive review emphasizes the evolving treatment landscape, particularly …

Background Metastatic breast cancer (MBC) behaviour differs depending on hormone
receptors (HR) and human epidermal growth factor receptor (HER2) statuses. Methods The …

The blood–brain barrier (BBB) represents a key challenge in develo** brain-penetrating
therapeutic molecules. BBB dysfunction is also associated with the onset and progression of …

Introduction Deep learning-based algorithms have demonstrated enormous performance in
segmentation of medical images. We collected a dataset of multiparametric MRI and contour …

The Blood–Brain Barrier (BBB) is a selective structural and functional barrier between the
circulatory system and the cerebral environment, playing an essential role in maintaining …