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Insight into the various approaches for the enhancement of bioavailability and pharmacological potency of terpenoids: a review
A Atriya, C Majee, R Mazumder… - Current …, 2023 - benthamdirect.com
Terpenoids are naturally occurring secondary metabolites that consist of isoprene units (ie, 2-
methyl-1, 3-butadiene). Terpenoids became recognized because of their diverse …
methyl-1, 3-butadiene). Terpenoids became recognized because of their diverse …
Nanoparticle-based flavonoid therapeutics: Pioneering biomedical applications in antioxidants, cancer treatment, cardiovascular health, neuroprotection, and …
HM Morsy, MY Zaky, NYS Yassin… - International Journal of …, 2024 - Elsevier
Flavonoids, a type of natural polyphenolic molecule, have garnered significant research
interest due to their ubiquitous nature and diverse biological activities, including antioxidant …
interest due to their ubiquitous nature and diverse biological activities, including antioxidant …
Cocrystal screening of anticancer drug p-toluenesulfonamide and preparation by supercritical antisolvent process
Abstract p-Toluenesulfonamide (PTS) is a new anticancer drug in development. Its poor
dissolution behavior complicates the design and development of the formulation process …
dissolution behavior complicates the design and development of the formulation process …
Uncovering Cocrystal Formation and Competition Mechanism of Polyhydroxy Natural Products: Cases of Quercetin, Hesperidin, Resveratrol, and Curcumin
D Li, W Chen, L Zhou, L Xu, F He, JYY Heng… - Crystal Growth & …, 2024 - ACS Publications
Understanding drug cocrystal formation and its competitive mechanism is important for
improving the physicochemical properties of drugs. In this article, the cocrystal formation of …
improving the physicochemical properties of drugs. In this article, the cocrystal formation of …
Supramolecular self-assembly strategy for the enhanced solubility/dissolution rate and anti-cancer efficacy of osimertinib: Insights from multi-component crystals to …
Multi-component crystal based on supramolecular self-assembly is an effective strategy to
modify the physicochemical properties of poorly water-soluble drugs. In this study, eight …
modify the physicochemical properties of poorly water-soluble drugs. In this study, eight …
Accelerated Wound Healing with a Diminutive Scar through Cocrystal Engineered Curcumin
Pharmaceutical cocrystals (Regulatory Classification of Pharmaceutical Co-Crystals
Guidance for Industry; Food and Drug Administration, 2018) are crystalline solids produced …
Guidance for Industry; Food and Drug Administration, 2018) are crystalline solids produced …
Theoretical simulation research on the hygroscopicity, stability, sensitivity, and mechanical properties of the cocrystals of ammonium nitrate with typical high energetic …
F Chen, D Liu, C Xuan, Q Lu, H Yang, L **ao… - Materials Today …, 2024 - Elsevier
Ammonium nitrate (AN) is a classical ionic salt that possesses thriving prospects in civil and
military fields. Nevertheless, the problems of multiple-phase transition and difficulty in …
military fields. Nevertheless, the problems of multiple-phase transition and difficulty in …
Pharmaceutical Properties of the Phloretin–4, 4′-Bipyridine Cocrystal: Structure Analysis, Drug Release Profile, and Antioxidant Activity Research
Z Lu, G Yao, H **e, D Wang, Y Chen, W Zhu - ACS omega, 2024 - ACS Publications
To improve the water solubility of phloretin, we synthesized the Phl–4B cocrystal using the
solvent evaporation method. Various analytical techniques including powder X-ray …
solvent evaporation method. Various analytical techniques including powder X-ray …
Theoretical exploration on the molecular configurations, solubilities and chemical reactivities of four flavonoid-based co-crystals
J Zhu, H Yao, Y Lu, H Lu, Z Liu, L Wang, X Zhao… - Journal of Molecular …, 2023 - Elsevier
Four flavonoid-based co-crystals containing the active pharmaceutical ingredients Apigenin
(AP), 4′, 7-Dihydroxyflavone (DH), Genistein (GE), Daidzein (DA) and the co-crystal former …
(AP), 4′, 7-Dihydroxyflavone (DH), Genistein (GE), Daidzein (DA) and the co-crystal former …
Phytosomes and herbosomes: a vesicular drug delivery system for improving the bioavailability of natural products
S Singh, YV Ushir, B Prajapati - Lipid-Based Drug Delivery …, 2023 - taylorfrancis.com
Natural products and secondary metabolites have been significantly investigated and
clinically tested for the treatment of various diseases in humans; however, their applications …
clinically tested for the treatment of various diseases in humans; however, their applications …