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Sepsis-induced immunosuppression: mechanisms, diagnosis and current treatment options
D Liu, SY Huang, JH Sun, HC Zhang, QL Cai… - Military Medical …, 2022 - Springer
Sepsis is a common complication of combat injuries and trauma, and is defined as a life-
threatening organ dysfunction caused by a dysregulated host response to infection. It is also …
threatening organ dysfunction caused by a dysregulated host response to infection. It is also …
2023 update on sepsis and septic shock in adult patients: management in the emergency department
Background: Sepsis/septic shock is a life-threatening and time-dependent condition that
requires timely management to reduce mortality. This review aims to update physicians with …
requires timely management to reduce mortality. This review aims to update physicians with …
SIRS, SOFA, qSOFA, and NEWS in the diagnosis of sepsis and prediction of adverse outcomes: a systematic review and meta-analysis
X Qiu, YP Lei, RX Zhou - Expert review of anti-infective therapy, 2023 - Taylor & Francis
ABSTRACT Background We compared Systemic Inflammatory Response Syndrome (SIRS),
Sequential Organ Failure Assessment (SOFA), Quick Sepsis-related Organ Failure …
Sequential Organ Failure Assessment (SOFA), Quick Sepsis-related Organ Failure …
Presepsin in the diagnosis of sepsis
T Paraskevas, C Chourpiliadi, S Demiri… - Clinica Chimica …, 2023 - Elsevier
Objectives Sepsis is a life-threatening condition characterized by organ dysfunction. It
occurs due to the host's dysregulated response to an infection. Clinicians use inflammatory …
occurs due to the host's dysregulated response to an infection. Clinicians use inflammatory …
New insights into the fluid management in patients with septic shock
CD Moschopoulos, D Dimopoulou, A Dimopoulou… - Medicina, 2023 - mdpi.com
The importance of fluid resuscitation therapy during the early stages of sepsis management
is a well-established principle. Current Surviving Sepsis Campaign (SSC) guidelines …
is a well-established principle. Current Surviving Sepsis Campaign (SSC) guidelines …
The implication of targeting PD-1: PD-L1 pathway in treating sepsis through immunostimulatory and anti-inflammatory pathways
Y Chen, D Guo, C Zhu, S Ren, C Sun, Y Wang… - Frontiers in …, 2023 - frontiersin.org
Sepsis currently remains a major contributor to mortality in the intensive care unit (ICU), with
48.9 million cases reported globally and a mortality rate of 22.5% in 2017, accounting for …
48.9 million cases reported globally and a mortality rate of 22.5% in 2017, accounting for …
Norepinephrine may exacerbate septic acute kidney injury: a narrative review
L Al-Husinat, A Alsabbah, AA Hmaid… - Journal of Clinical …, 2023 - mdpi.com
Sepsis, the most serious complication of infection, occurs when a cascade of potentially life-
threatening inflammatory responses is triggered. Potentially life-threatening septic shock is a …
threatening inflammatory responses is triggered. Potentially life-threatening septic shock is a …
Albumin as a prognostic marker of 30-day mortality in septic patients admitted to the emergency department
Background Assessing the evolutive risk of septic patients in the emergency department
(ED) is very complex. Predictive tools are available, but at an early stage, none of them can …
(ED) is very complex. Predictive tools are available, but at an early stage, none of them can …
A time series driven model for early sepsis prediction based on transformer module
Y Tang, Y Zhang, J Li - BMC Medical Research Methodology, 2024 - Springer
Sepsis remains a critical concern in intensive care units due to its high mortality rate. Early
identification and intervention are paramount to improving patient outcomes. In this study …
identification and intervention are paramount to improving patient outcomes. In this study …
Plac8-ERK pathway modulation of monocyte function in sepsis
T Zhang, J Fu, G Chen, X Zhang - Cell Death Discovery, 2024 - nature.com
Sepsis, a life-threatening condition caused by infection, is characterized by the
dysregulation of immune responses and activation of monocytes. Plac8, a protein, has been …
dysregulation of immune responses and activation of monocytes. Plac8, a protein, has been …