The new genetics of intelligence

R Plomin, S Von Stumm - Nature Reviews Genetics, 2018 - nature.com
Intelligence—the ability to learn, reason and solve problems—is at the forefront of
behavioural genetic research. Intelligence is highly heritable and predicts important …

Analysis of shared heritability in common disorders of the brain

Brainstorm Consortium, V Anttila, B Bulik-Sullivan… - Science, 2018 - science.org
INTRODUCTION Brain disorders may exhibit shared symptoms and substantial
epidemiological comorbidity, inciting debate about their etiologic overlap. However, detailed …

Analysis of shared heritability in common disorders of the brain

Brainstorm Consortium - Science (New York, NY), 2018 - pmc.ncbi.nlm.nih.gov
INTRODUCTION: Brain disorders may exhibit shared symptoms and substantial epidemio-
logical comorbidity, inciting debate about their etiologic overlap. However, detailed study of …

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

G Davies, M Lam, SE Harris, JW Trampush… - Nature …, 2018 - nature.com
General cognitive function is a prominent and relatively stable human trait that is associated
with many important life outcomes. We combine cognitive and genetic data from the …

A comparison of the prevalence of dementia in the United States in 2000 and 2012

KM Langa, EB Larson, EM Crimmins… - JAMA internal …, 2017 - jamanetwork.com
Importance The aging of the US population is expected to lead to a large increase in the
number of adults with dementia, but some recent studies in the United States and other high …

Concepts, estimation and interpretation of SNP-based heritability

J Yang, J Zeng, ME Goddard, NR Wray, PM Visscher - Nature genetics, 2017 - nature.com
Abstract Narrow-sense heritability (h 2) is an important genetic parameter that quantifies the
proportion of phenotypic variance in a trait attributable to the additive genetic variation …

The advantages and limitations of trait analysis with GWAS: a review

A Korte, A Farlow - Plant methods, 2013 - Springer
Over the last 10 years, high-density SNP arrays and DNA re-sequencing have illuminated
the majority of the genotypic space for a number of organisms, including humans, maize …

Genetics and intelligence differences: five special findings

R Plomin, IJ Deary - Molecular psychiatry, 2015 - nature.com
Intelligence is a core construct in differential psychology and behavioural genetics, and
should be so in cognitive neuroscience. It is one of the best predictors of important life …

Reevaluation of SNP heritability in complex human traits

D Speed, N Cai, Ucleb Consortium, MR Johnson… - Nature …, 2017 - nature.com
SNP heritability, the proportion of phenotypic variance explained by SNPs, has been
reported for many hundreds of traits. Its estimation requires strong prior assumptions about …

Successful memory aging

L Nyberg, S Pudas - Annual review of psychology, 2019 - annualreviews.org
For more than 50 years, psychologists, gerontologists, and, more recently, neuroscientists
have considered the possibility of successful aging. How to define successful aging remains …