The new genetics of intelligence
Intelligence—the ability to learn, reason and solve problems—is at the forefront of
behavioural genetic research. Intelligence is highly heritable and predicts important …
behavioural genetic research. Intelligence is highly heritable and predicts important …
Analysis of shared heritability in common disorders of the brain
INTRODUCTION Brain disorders may exhibit shared symptoms and substantial
epidemiological comorbidity, inciting debate about their etiologic overlap. However, detailed …
epidemiological comorbidity, inciting debate about their etiologic overlap. However, detailed …
Analysis of shared heritability in common disorders of the brain
Brainstorm Consortium - Science (New York, NY), 2018 - pmc.ncbi.nlm.nih.gov
INTRODUCTION: Brain disorders may exhibit shared symptoms and substantial epidemio-
logical comorbidity, inciting debate about their etiologic overlap. However, detailed study of …
logical comorbidity, inciting debate about their etiologic overlap. However, detailed study of …
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
General cognitive function is a prominent and relatively stable human trait that is associated
with many important life outcomes. We combine cognitive and genetic data from the …
with many important life outcomes. We combine cognitive and genetic data from the …
A comparison of the prevalence of dementia in the United States in 2000 and 2012
Importance The aging of the US population is expected to lead to a large increase in the
number of adults with dementia, but some recent studies in the United States and other high …
number of adults with dementia, but some recent studies in the United States and other high …
Concepts, estimation and interpretation of SNP-based heritability
Abstract Narrow-sense heritability (h 2) is an important genetic parameter that quantifies the
proportion of phenotypic variance in a trait attributable to the additive genetic variation …
proportion of phenotypic variance in a trait attributable to the additive genetic variation …
The advantages and limitations of trait analysis with GWAS: a review
Over the last 10 years, high-density SNP arrays and DNA re-sequencing have illuminated
the majority of the genotypic space for a number of organisms, including humans, maize …
the majority of the genotypic space for a number of organisms, including humans, maize …
Genetics and intelligence differences: five special findings
Intelligence is a core construct in differential psychology and behavioural genetics, and
should be so in cognitive neuroscience. It is one of the best predictors of important life …
should be so in cognitive neuroscience. It is one of the best predictors of important life …
Reevaluation of SNP heritability in complex human traits
SNP heritability, the proportion of phenotypic variance explained by SNPs, has been
reported for many hundreds of traits. Its estimation requires strong prior assumptions about …
reported for many hundreds of traits. Its estimation requires strong prior assumptions about …
Successful memory aging
For more than 50 years, psychologists, gerontologists, and, more recently, neuroscientists
have considered the possibility of successful aging. How to define successful aging remains …
have considered the possibility of successful aging. How to define successful aging remains …