A review of neurostimulation for epilepsy in pediatrics

K Starnes, K Miller, L Wong-Kisiel, BN Lundstrom - Brain sciences, 2019 - mdpi.com
Neurostimulation for epilepsy refers to the application of electricity to affect the central
nervous system, with the goal of reducing seizure frequency and severity. We review the …

A systematic review of deep brain stimulation for the treatment of drug-resistant epilepsy in childhood

H Yan, E Toyota, M Anderson, TJ Abel… - Journal of …, 2018 - thejns.org
OBJECTIVE Drug-resistant epilepsy (DRE) presents a therapeutic challenge in children,
necessitating the consideration of multiple treatment options. Although deep brain …

Centromedian thalamic responsive neurostimulation for Lennox‐Gastaut epilepsy and autism

CS Kwon, AJ Schupper, MC Fields… - Annals of Clinical …, 2020 - Wiley Online Library
The RNS System is not approved in patients under 18, although a critical need for novel
treatment modalities in this vulnerable population persist. We present two pediatric patients …

Case report: responsive neurostimulation of the centromedian thalamic nucleus for the detection and treatment of seizures in pediatric primary generalized epilepsy

WP Welch, JL Hect, TJ Abel - Frontiers in Neurology, 2021 - frontiersin.org
Up to 20% of pediatric patients with primary generalized epilepsy (PGE) will not respond
effectively to medication for seizure control. Responsive neurostimulation (RNS) is a …

Neuromodulation for the treatment of epilepsy: a review of current approaches and future directions

P Davis, J Gaitanis - Clinical Therapeutics, 2020 - Elsevier
Purpose Neuromodulation holds great promise for the treatment of drug-resistant epilepsy.
This article reviews the most common types of neuromodulation as well as potential future …

Responsive neurostimulation targeting the anterior, centromedian and pulvinar thalamic nuclei and the detection of electrographic seizures in pediatric and young …

CP Beaudreault, CR Muh, A Naftchi… - Frontiers in Human …, 2022 - frontiersin.org
Background Responsive neurostimulation (RNS System) has been utilized as a treatment
for intractable epilepsy. The RNS System delivers stimulation in response to detected …

Safety and efficacy of responsive neurostimulation in the pediatric population: evidence from institutional review and patient-level meta-analysis

P Kerezoudis, A Gyftopoulos, AY Alexander… - Epilepsy & Behavior, 2022 - Elsevier
Background Responsive neurostimulation (RNS) is a novel technology for drug-resistant
epilepsy rising from bilateral hemispheres or eloquent cortex. Although recently approved …

Responsive neurostimulation: candidates and considerations

BB Ma, VR Rao - Epilepsy & Behavior, 2018 - Elsevier
Responsive neurostimulation (RNS) has recently emerged as a safe and effective treatment
for some patients with medically refractory focal epilepsy who are not candidates for surgical …

Safety of responsive neurostimulation in pediatric patients with medically refractory epilepsy

F Panov, S Ganaha, J Haskell, M Fields… - Journal of …, 2020 - thejns.org
OBJECTIVE Approximately 75% of pediatric patients who suffer from epilepsy are
successfully treated with antiepileptic drugs, while the disease is drug resistant in the …

Real-world preliminary experience with responsive neurostimulation in pediatric epilepsy: a multicenter retrospective observational study

Y Nagahama, TM Zervos, KK Murata, L Holman… - …, 2021 - journals.lww.com
Real-World Preliminary Experience With Responsive Neurostimu... : Neurosurgery Real-World
Preliminary Experience With Responsive Neurostimulation in Pediatric Epilepsy: A …