Current status of hand-foot-and-mouth disease

P Zhu, W Ji, D Li, Z Li, Y Chen, B Dai, S Han… - Journal of biomedical …, 2023 - Springer
Hand-foot-and-mouth disease (HFMD) is a viral illness commonly seen in young children
under 5 years of age, characterized by typical manifestations such as oral herpes and …

Recent progress on the versatility of virus-like particles

C Qian, X Liu, Q Xu, Z Wang, J Chen, T Li, Q Zheng… - Vaccines, 2020 - mdpi.com
Virus-like particles (VLPs) are multimeric nanostructures composed of one or more structural
proteins of a virus in the absence of genetic material. Having similar morphology to natural …

Hand-foot-and-mouth disease-associated enterovirus and the development of multivalent HFMD vaccines

X Zhang, Y Zhang, H Li, L Liu - International Journal of Molecular …, 2022 - mdpi.com
Hand-foot-and-mouth disease (HFMD) is an infectious disease of children caused by more
than 20 types of enteroviruses, with most cases recovering spontaneously within …

Enterovirus A71 vaccines

ML Li, SR Shih, BS Tolbert, G Brewer - Vaccines, 2021 - mdpi.com
Enterovirus A71 (EV-A71) is a major causative agent of hand, foot, and mouth disease
(HFMD) and herpangina. Moreover, EV-A71 infection can lead to neurological complications …

Enteroviruses: epidemic potential, challenges and opportunities with vaccines

M Jartti, M Flodström-Tullberg… - Journal of Biomedical …, 2024 - Springer
Enteroviruses (EVs) are the most prevalent viruses in humans. EVs can cause a range of
acute symptoms, from mild common colds to severe systemic infections such as meningitis …

[HTML][HTML] Effectiveness of EV-A71 Vaccine and Its Impact on the Incidence of Hand, Foot and Mouth Disease: A Systematic Review

Q Hu, Y **e, F Ji, F Zhao, X Song, S Lu, Z Li, J Geng… - Vaccines, 2024 - mdpi.com
Background: Vaccination is a highly effective strategy for the prevention of enterovirus A71
(EV-A71)—hand, foot, and mouth disease (HFMD). Three inactivated EV-A71 vaccines in …

A review and meta‐analysis of the epidemiology and clinical presentation of coxsackievirus A6 causing hand‐foot‐mouth disease in China and global implications

TS Zhao, J Du, DP Sun, QR Zhu… - Reviews in medical …, 2020 - Wiley Online Library
Summary Coxsackievirus A6 (CV‐A6) has been associated with increasingly occurred
sporadic hand‐foot‐mouth disease (HFMD) cases and outbreak events in many countries. In …

From monovalent to multivalent vaccines, the exploration for potential preventive strategies against hand, foot, and mouth disease (HFMD)

X He, M Zhang, C Zhao, P Zheng, X Zhang, J Xu - Virologica Sinica, 2021 - Springer
Hand, foot, and mouth disease (HFMD) recently emerged as a global public threat. The
licensure of inactivated enterovirus A71 (EV-A71) vaccine was the first step in using a …

Recent development of enterovirus A vaccine candidates for the prevention of hand, foot, and mouth disease

CY Fang, CC Liu - Expert review of vaccines, 2018 - Taylor & Francis
Introduction: Hand, foot, and mouth disease (HFMD) is a childhood illness commonly
caused by enterovirus A. Enterovirus A71 (EV-A71) and coxsackievirus A16 (CV-A16) are …

Advances in antigenic peptide-based vaccine and neutralizing antibodies against viruses causing hand, foot, and mouth disease

MI Anasir, CL Poh - International Journal of Molecular Sciences, 2019 - mdpi.com
Hand, foot, and mouth disease (HFMD) commonly produces herpangina, but fatal
neurological complications have been observed in children. Enterovirus 71 (EV-A71) and …