Solid-state NMR spectroscopic techniques provide valuable information about the structure,
dynamics and topology of membrane-inserted polypeptides. In particular antimicrobial …

Antimicrobial peptides (AMPs) are short molecules produced by almost all organisms. Fish
AMPs contain innate immune components as their primary immune molecules. The fish …

While antimicrobial peptides (AMPs) have been widely investigated as potential
therapeutics, high-resolution structures obtained under biologically relevant conditions are …

Antimicrobial peptides (AMPs) that disrupt bacterial membranes are promising therapeutics
against the growing number of antibiotic-resistant bacteria. The mechanism of membrane …

Piscidin-1 (Pis-1) is a linear antibacterial peptide derived from mast cells of aquacultured
hybrid striped bass that comprises 22 amino acids with a phenylalanine-rich amino …

A new class of antimicrobial agents with lower rates of resistance and different targets is
urgently needed because of the rapidly increasing resistance to classical antibiotics …

Piscidins were the first antimicrobial peptides discovered in the mast cells of vertebrates.
While two family members, piscidin 1 (p1) and piscidin 3 (p3), have highly similar sequences …

In the search for novel broad-spectrum therapeutics to fight chronic infections, inflammation,
and cancer, host defense peptides (HDPs) have garnered increasing interest …

Abstract Gad-1 and Gad-2 are antimicrobial peptide (AMP) sequences encoded by
paralogous genes. They are rich in histidine, which suggests that their activity might be pH …

The amino-terminal-copper-and-nickel-binding (ATCUN) motif, a tripeptide sequence
ending with a histidine, confers important functions to proteins and peptides. Few high …