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Evolutionarily divergent mTOR remodels translatome for tissue regeneration
O Zhulyn, HD Rosenblatt, L Shokat, S Dai… - Nature, 2023 - nature.com
An outstanding mystery in biology is why some species, such as the axolotl, can regenerate
tissues whereas mammals cannot. Here, we demonstrate that rapid activation of protein …
tissues whereas mammals cannot. Here, we demonstrate that rapid activation of protein …
Nutrition-and hormone-controlled developmental plasticity in Blattodea
Highlights•The IIS/TORC1 and MEKRE93 pathways coordinately regulate body size by
regulating nymphal growth, molting, and metamorphosis;•Blattodea insects have evolved …
regulating nymphal growth, molting, and metamorphosis;•Blattodea insects have evolved …
To regenerate or not to regenerate: Vertebrate model organisms of regeneration‐competency and‐incompetency
Why only certain species can regenerate their appendages (eg tails and limbs) remains one
of the biggest mysteries of nature. Unlike anuran tadpoles and salamanders, humans and …
of the biggest mysteries of nature. Unlike anuran tadpoles and salamanders, humans and …
A novel approach to comparative RNA-seq does not support a conserved set of orthologs underlying animal regeneration
Molecular studies of animal regeneration typically focus on conserved genes and signaling
pathways that underlie morphogenesis. To date, a holistic analysis of gene expression …
pathways that underlie morphogenesis. To date, a holistic analysis of gene expression …
Evolution and Function of the Notch Signaling Pathway: An Invertebrate Perspective
The highly conserved Notch signaling pathway affects embryonic development,
neurogenesis, homeostasis, tissue repair, immunity, and numerous other essential …
neurogenesis, homeostasis, tissue repair, immunity, and numerous other essential …
Insulin-like signaling promotes limb regeneration in the Chinese mitten crab (Eriocheir sinensis)
J Li, Y Tian, X Li, J Zuo, R Zhao, J Sun - Fish & Shellfish Immunology, 2022 - Elsevier
In the pond culture of Chinese mitten crabs, limb autotomy seriously affects the feeding
efficiency, immunity and survival. Therefore, it is crucial to understand the mechanism of limb …
efficiency, immunity and survival. Therefore, it is crucial to understand the mechanism of limb …
Toeing the line between regeneration and fibrosis
V Jou, JA Lehoczky - Frontiers in Cell and Developmental Biology, 2023 - frontiersin.org
Understanding the remarkable capacity of vertebrates to naturally regenerate injured body
parts has great importance for potential translation into human therapeutic applications. As …
parts has great importance for potential translation into human therapeutic applications. As …
The microbiome of a Pacific moon jellyfish Aurelia coerulea
AH Ohdera, M Mansbridge, M Wang, P Naydenkov… - Plos one, 2024 - journals.plos.org
The impact of microbiome in animal physiology is well appreciated, but characterization of
animal-microbe symbiosis in marine environments remains a growing need. This study …
animal-microbe symbiosis in marine environments remains a growing need. This study …
Mammalian organ regeneration in spiny mice
DM Okamura, ED Nguyen, SJ Collins, K Yoon… - Journal of Muscle …, 2023 - Springer
Fibrosis-driven solid organ failure is a major world-wide health burden with few therapeutic
options. Spiny mice (genus: Acomys) are terrestrial mammals that regenerate severe skin …
options. Spiny mice (genus: Acomys) are terrestrial mammals that regenerate severe skin …
Multiphysics discovery with moving boundaries using Ensemble SINDy and peridynamic differential operator
This study proposes a novel framework for learning the underlying physics of phenomena
with moving boundaries. The proposed approach combines Ensemble SINDy and …
with moving boundaries. The proposed approach combines Ensemble SINDy and …