Advancements in transdermal drug delivery: A comprehensive review of physical penetration enhancement techniques

SS Gaikwad, AL Zanje, JD Somwanshi - International Journal of …, 2024 - Elsevier
Transdermal drug administration has grown in popularity in the pharmaceutical research
community due to its potential to improve drug bioavailability, compliance among patients …

Feasibility of laser induced jets in needle free jet injections

P Rohilla, J Marston - International journal of pharmaceutics, 2020 - Elsevier
This paper reports a detailed characterization of laser-induced micro-jets, including ex vivo
experiments using skin as a target substrate to check the feasibility in terms of needle-free …

Impact of the mechanical properties of penetrated media on the injection characteristics of needle-free jet injection

A Mohizin, D Lee, JK Kim - Experimental Thermal and Fluid Science, 2021 - Elsevier
Needle-free jet injection systems are characterized by the increased drug delivery efficacy
over conventional needle-based injection systems and have become a viable alternative …

Clinical endpoints of needle‐free jet injector treatment: An in depth understanding of immediate skin responses

L Bik, MBA van Doorn, N Boei**k… - Lasers in surgery …, 2022 - Wiley Online Library
Objectives Needle‐free jet injectors have been used in dermatological practice for many
years. However, predefined clinical endpoints that guide physicians to choose optimal …

[HTML][HTML] Duck plague virus infection alter the microbiota composition and intestinal functional activity in Muscovy ducks

J Kong, X Wu, L Liao, Z **e, K Feng, F Chen, X Zhang… - Poultry Science, 2023 - Elsevier
Intestinal damage from the duck plague virus (DPV) infection affects intestinal inflammation
factors expression and barrier dysfunction. Here we report findings from the pathogenicity of …

Dynamic interaction of injected liquid jet with skin layer interfaces revealed by microsecond imaging of optically cleared ex vivo skin tissue model

A Mohizin, JH Imran, KS Lee, JK Kim - Journal of Biological Engineering, 2023 - Springer
Background Needle-free jet injection (NFJI) systems enable a controlled and targeted
delivery of drugs into skin tissue. However, a scarce understanding of their underlying …

Design and analysis: Servo-tube-powered liquid jet injector for drug delivery applications

R Portaro, HD Ng - Applied Sciences, 2022 - mdpi.com
The current state of commercially available needle-free liquid jet injectors for drug delivery
offers no way of controlling the output pressure of the device in real time, as the driving …

[HTML][HTML] Potent intradermal gene expression of naked plasmid DNA in pig skin following pyro-drive jet injection

H Miyazaki, Y Sakaguchi, K Terai - Journal of Pharmaceutical Sciences, 2021 - Elsevier
Intradermal administration of naked DNA with a conventional needle syringe is a simple and
inexpensive method to expose an encoded antigen to the dermal immune system. We …

A novel controllable pneumatic needle-free injection system for larger-volume drug delivery

D Zeng, N Wu, L Qian, H Shi, Y Kang - Journal of Pharmaceutical Sciences, 2020 - Elsevier
Hypodermic needles and syringes are currently the main route of the transdermal
administration. Many complaints associated with needle-stick injuries, needle phobia, and …

Experimental investigation of the optimal driving pressure for a larger-volume controllable jet injection system

D Zeng, Z Tang, W Wang, Z Wang, J Li - Medical Engineering & Physics, 2023 - Elsevier
Jet injection technology has become the alternative drug delivery method of conventional
needle-based injection due to its obvious advantages. In order to meet the demand for …