[HTML][HTML] Extraintestinal Pathogenic Escherichia coli: Virulence Factors and Antibiotic Resistance

VM Sora, G Meroni, PA Martino, A Soggiu, L Bonizzi… - Pathogens, 2021‏ - mdpi.com
The One Health approach emphasizes the importance of antimicrobial resistance (AMR) as
a major concern both in public health and in food animal production systems. As a general …

The OmpA family of proteins: roles in bacterial pathogenesis and immunity

AW Confer, S Ayalew - Veterinary microbiology, 2013‏ - Elsevier
The OmpA family of outer membrane proteins is a group of genetically related, heat-
modifiable, surface-exposed, porin proteins that are in high-copy number in the outer …

Electroporation of the E. coli and S. aureus membranes: molecular dynamics simulations of complex bacterial membranes

TJ Piggot, DA Holdbrook, S Khalid - The journal of physical …, 2011‏ - ACS Publications
Bacterial membranes are complex organelles composed of a variety of lipid types. The
differences in their composition are a key factor in determining their relative permeabilities …

Molecular dynamics simulations of phosphatidylcholine membranes: a comparative force field study

TJ Piggot, A Pineiro, S Khalid - Journal of chemical theory and …, 2012‏ - ACS Publications
Molecular dynamics simulations provide a route to studying the dynamics of lipid bilayers at
atomistic or near atomistic resolution. Over the past 10 years or so, molecular dynamics …

Outer Membrane Proteins and Efflux Pumps Mediated Multi-Drug Resistance in Salmonella: Rising Threat to Antimicrobial Therapy

SD Akshay, VK Deekshit, J Mohan Raj… - ACS Infectious …, 2023‏ - ACS Publications
Despite colossal achievements in antibiotic therapy in recent decades, drug-resistant
pathogens have remained a leading cause of death and economic loss globally. One such …

Outer membrane proteins of Pasteurella multocida

T Hatfaludi, K Al-Hasani, JD Boyce, B Adler - Veterinary microbiology, 2010‏ - Elsevier
Pasteurella multocida is a ubiquitous pathogen which causes a range of diseases in diverse
animal species. Components of the bacterial outer membrane, such as trans membrane …

Outer membrane protein G: Engineering a quiet pore for biosensing

M Chen, S Khalid, MSP Sansom, H Bayley - Proceedings of the National …, 2008‏ - pnas.org
Bacterial outer membrane porins have a robust β-barrel structure and therefore show
potential for use as stochastic sensors based on single-molecule detection. The monomeric …

Transmembrane domain of surface-exposed outer membrane lipoprotein RcsF is threaded through the lumen of β-barrel proteins

A Konovalova, DH Perlman, CE Cowles… - Proceedings of the …, 2014‏ - pnas.org
RcsF (regulator of capsule synthesis) is an outer membrane (OM) lipoprotein that functions
to sense defects such as changes in LPS. However, LPS is found in the outer leaflet, and …

Mannheimia haemolytica in bovine respiratory disease: immunogens, potential immunogens, and vaccines

AW Confer, S Ayalew - Animal health research reviews, 2018‏ - cambridge.org
Mannheimia haemolytica is the major cause of severe pneumonia in bovine respiratory
disease (BRD). Early M. haemolytica bacterins were either ineffective or even enhanced …

[HTML][HTML] Gating of β-barrel protein pores, porins, and channels: an old problem with new facets

LA Mayse, L Movileanu - International journal of molecular sciences, 2023‏ - mdpi.com
β barrels are ubiquitous proteins in the outer membranes of mitochondria, chloroplasts, and
Gram-negative bacteria. These transmembrane proteins (TMPs) execute a wide variety of …