Alzheimer's disease as a synaptopathy: Evidence for dysfunction of synapses during disease progression

S Meftah, J Gan - Frontiers in Synaptic Neuroscience, 2023 - frontiersin.org
The synapse has consistently been considered a vulnerable and critical target within
Alzheimer's disease, and synapse loss is, to date, one of the main biological correlates of …

[HTML][HTML] An update on the use of gamma (multi) sensory stimulation for Alzheimer's disease treatment

V Manippa, A Palmisano, M Filardi, D Vilella… - Frontiers in Aging …, 2022 - frontiersin.org
Alzheimer's disease (AD) is characterized by reduced fast brain oscillations in the gamma
band (γ,> 30 Hz). Several animal studies show that inducing gamma oscillations through …

Gamma entrainment using audiovisual stimuli alleviates chemobrain pathology and cognitive impairment induced by chemotherapy in mice

TH Kim, BT James, MC Kahn… - Science Translational …, 2024 - science.org
Patients with cancer undergoing chemotherapy frequently experience a neurological
condition known as chemotherapy-related cognitive impairment, or “chemobrain,” which can …

40 Hz light flickering promotes sleep through cortical adenosine signaling

X Zhou, Y He, T Xu, Z Wu, W Guo, X Xu, Y Liu, Y Zhang… - Cell Research, 2024 - nature.com
Flickering light stimulation has emerged as a promising non-invasive neuromodulation
strategy to alleviate neuropsychiatric disorders. However, the lack of a neurochemical …

Transcranial alternating current stimulation (tACS) at gamma frequency: an up-and-coming tool to modify the progression of Alzheimer's Disease

ML De Paolis, I Paoletti, C Zaccone, F Capone… - Translational …, 2024 - Springer
The last decades have witnessed huge efforts devoted to deciphering the pathological
mechanisms underlying Alzheimer's Disease (AD) and to testing new drugs, with the recent …

Alzheimer's disease: A review on the current trends of the effective diagnosis and therapeutics

AS Abdul Manap, R Almadodi, S Sultana… - Frontiers in Aging …, 2024 - frontiersin.org
The most prevalent cause of dementia is Alzheimer's disease. Cognitive decline and
accelerating memory loss characterize it. Alzheimer's disease advances sequentially …

[HTML][HTML] 40-Hz optogenetic stimulation rescues functional synaptic plasticity after stroke

C Wang, C Lin, Y Zhao, M Samantzis, P Sedlak, P Sah… - Cell reports, 2023 - cell.com
Evoked brain oscillations in the gamma range have been shown to assist in stroke recovery.
However, the causal relationship between evoked oscillations and neuroprotection is not …

[HTML][HTML] Alzheimer's disease and sleep disorders: a bidirectional relationship

J Chen, G Peng, B Sun - Neuroscience, 2024 - Elsevier
Alzheimer's disease (AD) is the most prevalent dementia, pathologically featuring abnormal
accumulation of amyloid-β (A β) and hyperphosphorylated tau, while sleep, divided into …

Theta and gamma oscillatory dynamics in mouse models of Alzheimer's disease: A path to prospective therapeutic intervention

SF Mehak, AB Shivakumar, S Kumari… - Neuroscience & …, 2022 - Elsevier
Understanding the neural basis of cognitive deficits, a key feature of Alzheimer's disease
(AD), is imperative for achieving the therapy of the disease. Rhythmic oscillatory activities in …

Advances in photobiomodulation for cognitive improvement by near-infrared derived multiple strategies

W Pan, P Liu, D Ma, J Yang - Journal of Translational Medicine, 2023 - Springer
Cognitive function is an important ability of the brain, but cognitive dysfunction can easily
develop once the brain is injured in various neuropathological conditions or diseases …