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3,322,756 A 5, 1967 Hilmer et al. 3,544,570 A 12/1970 Trimmler et al. 3,823,135 A 7/1974
Pilgram et al. 3,960,949 A 6, 1976 Ahrens et al. 4,494,978 A 1, 1985 Chan 4,687,777 A …

New quinazoline-sulfonylurea hybrids were prepared and examined for their in vivo anti-
hyperglycemic activities in STZ-induced hyperglycemic rats using glibenclamide as a …

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6.258, 597 B1 7/2001 Bachovchin 626,794 B 72001 Chang 2002/0049164 A1 4/2002
Demuth et al. 6,265.55 B 72001 Duke Cohan et al. 2002/0061839 A1 5/2002 Scharpe et al …

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Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV and other
S9 proteases that comprise a compound comprising: wherein M is N or CR; Q'and Q are …

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US PATENT DOCUMENTS 3,322,756 A 5, 1967 Hilmer et al. 3,544,570 A 12/1970 Timmler
et al. 3,823,135 A 7/1974 Pilgram et al. 3,960,949 A 6, 1976 Ahrens et al. 4,494,978 A 1 …