Drugs with low water solubility are predisposed to low and variable oral bioavailability and,
therefore, to variability in clinical response. Despite significant efforts to “design in” …

Low drug bioavailability, which is mostly a result of poor aqueous drug solubilities and of
inadequate drug dissolution rates, is one of the most significant challenges that …

The CRC Handbook of Solubility Parameters and Other Cohesion Parameters, Second
Edition, which includes 17 new sections and 40 new data tables, incorporates information …

The main goal of the present paper is to assess the available information so as to obtain a
general procedure for dealing with the critical enhancement of the thermodynamic and …

The ability to correlate and predict the solubility of solids in supercritical fluids is important in
many applications, including solid deposition in natural gases and the supercritical …

Synthesizing research from a wide variety of sources, this work offers a convenient guide to
a clean, safe, inexpensive, non-toxic, non-polluting solvent that performs better than most …

Supercritical fluid extraction is an environmentally safe and cost-effective alternative to
traditional organic solvents. Carbon dioxide is widely used as the solvent of choice for …

The enormous quantity of food wastes discarded annually forces a look into alternatives for
this interesting feedstock. Thus, food bio-waste valorisation is one of the current imperatives …

Nile Red was used as a solvatochromic probe to measure the solvent strength of 85 pure
liquids and the results were com-pared to solvent strength scales from the better known Rel …

Supercritical fluid extraction (SCFE), based on the utilization of a fluid under supercritical
conditions, is a technology suitable for extraction and purification of a variety of compounds …