[HTML][HTML] Antimicrobial peptides: an emerging category of therapeutic agents

M Mahlapuu, J Håkansson, L Ringstad… - Frontiers in cellular and …, 2016 - frontiersin.org
Antimicrobial peptides (AMPs), also known as host defense peptides, are short and
generally positively charged peptides found in a wide variety of life forms from …

Polymyxins: antibacterial activity, susceptibility testing, and resistance mechanisms encoded by plasmids or chromosomes

L Poirel, A Jayol, P Nordmann - Clinical microbiology reviews, 2017 - Am Soc Microbiol
Polymyxins are well-established antibiotics that have recently regained significant interest
as a consequence of the increasing incidence of infections due to multidrug-resistant Gram …

Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria?

KA Brogden - Nature reviews microbiology, 2005 - nature.com
Antimicrobial peptides are an abundant and diverse group of molecules that are produced
by many tissues and cell types in a variety of invertebrate, plant and animal species. Their …

[HTML][HTML] Antimicrobial peptides

L Zhang, RL Gallo - Current biology, 2016 - cell.com
Antimicrobial peptides and proteins (AMPs) are a diverse class of naturally occurring
molecules that are produced as a first line of defense by all multicellular organisms. These …

Peptide antimicrobial agents

H Jenssen, P Hamill, REW Hancock - Clinical microbiology …, 2006 - Am Soc Microbiol
Antimicrobial host defense peptides are produced by all complex organisms as well as
some microbes and have diverse and complex antimicrobial activities. Collectively these …

Antimicrobial peptides, conventional antibiotics, and their synergistic utility for the treatment of drug‐resistant infections

Y Zhu, W Hao, X Wang, J Ouyang… - Medicinal Research …, 2022 - Wiley Online Library
Antimicrobial peptides (AMPs), also known as host defense peptides (HDPs), are important
effector immune defense molecules in multicellular organisms. AMPs exert their …

Antimicrobial peptides as anticancer agents: functional properties and biological activities

AL Tornesello, A Borrelli, L Buonaguro, FM Buonaguro… - Molecules, 2020 - mdpi.com
Antimicrobial peptides (AMPs), or host defense peptides, are small cationic or amphipathic
molecules produced by prokaryotic and eukaryotic organisms that play a key role in the …

Peptide antibiotics

REW Hancock, DS Chapple - Antimicrobial agents and …, 1999 - Am Soc Microbiol
Hundreds of peptide antibiotics have been described in the past half-century (20, 28, 35).
These fall into two classes, nonribosomally synthesized peptides, such as the gramicidins …

[HTML][HTML] LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity

A Krause, S Neitz, HJ Mägert, A Schulz… - FEBS letters, 2000 - Elsevier
We report the isolation and characterization of a novel human peptide with antimicrobial
activity, termed LEAP-1 (liver-expressed antimicrobial peptide). Using a mass spectrometric …

Cationic peptides: a new source of antibiotics

REW Hancock, R Lehrer - Trends in biotechnology, 1998 - cell.com
Antimicrobial cationic peptides are an important component of the innate defenses of all
species of life. Different peptides may have antibacterial, antiendotoxic, antibiotic …