Effects of pre-natal alcohol exposure on hippocampal synaptic plasticity: Sex, age and methodological considerations

CJ Fontaine, AR Patten, HM Sickmann, JL Helfer… - Neuroscience & …, 2016 - Elsevier
The consumption of alcohol during gestation is detrimental to the develo** central
nervous system (CNS). The severity of structural and functional brain alterations associated …

Synaptic plasticity abnormalities in fetal alcohol spectrum disorders

BS Basavarajappa, S Subbanna - Cells, 2023 - mdpi.com
The brain's ability to strengthen or weaken synaptic connections is often termed synaptic
plasticity. It has been shown to function in brain remodeling following different types of brain …

Dose‐dependent effects of prenatal ethanol exposure on synaptic plasticity and learning in mature offspring

DD Savage, M Becher, AJ de la Torre… - Alcoholism: Clinical …, 2002 - Wiley Online Library
Background We have observed profound deficits in hippocampal synaptic plasticity and one‐
trial learning in offspring whose mothers drank moderate quantities of ethanol during …

Hippocampal N‐Methyl‐d‐Aspartate Receptor Subunit Expression Profiles in a Mouse Model of Prenatal Alcohol Exposure

SL Samudio‐Ruiz, AM Allan, S Sheema… - Alcoholism: Clinical …, 2010 - Wiley Online Library
Background: Although several reports have been published showing prenatal ethanol
exposure is associated with alterations in N‐methyl‐d‐aspartate (NMDA) receptor subunit …

Effect of prenatal ethanol exposure on the developmental profile of the NMDA receptor subunits in rat forebrain and hippocampus

PD Hughes, YN Kim, PK Randall… - Alcoholism: Clinical …, 1998 - Wiley Online Library
The effects of prenatal ethanol exposure on the NMDARl protein expression (postnatal days
1 and 7) and on the developmental profile of the NMDAR2A and NMDAR2B subunits in rat …

MK‐801 administration during ethanol withdrawal in neonatal rat pups attenuates ethanol‐induced behavioral deficits

JD Thomas, SP Weinert, S Sharif… - Alcoholism: Clinical and …, 1997 - Wiley Online Library
Alcohol exposure during development can produce central nervous system dysfunction,
resulting in a wide range of behavioral alterations. The various mechanisms by which …

Neonatal ethanol exposure reduces AMPA but not NMDA receptor levels in the rat neocortex

FP Bellinger, MS Davidson, KS Bedi… - Developmental Brain …, 2002 - Elsevier
Fetal alcohol syndrome (FAS) is the leading cause of mental retardation in western society.
We investigated possible changes in glutamate receptor levels in neonatal animals …

Fetal alcohol exposure impairs alveolar macrophage function via decreased glutathione availability

TW Gauthier, XD **, FL Harris, M Wong… - Pediatric …, 2005 - nature.com
Immature function of the alveolar macrophage increases the risk of pulmonary infections in
premature newborns. In utero alcohol increases fetal systemic oxidative stress. Because the …

Spatial acquisition in the Morris water maze and hippocampal long-term potentiation in the adult guinea pig following brain growth spurt–prenatal ethanol exposure

ML Byrnes, DP Richardson, JF Brien… - Neurotoxicology and …, 2004 - Elsevier
Previous work has demonstrated that in the guinea pig, chronic prenatal ethanol exposure
throughout gestation can result in deficits in spatial learning in the Morris water maze and …

Effects of chronic prenatal ethanol exposure on locomotor activity, and hippocampal weight, neurons, and nitric oxide synthase activity of the young postnatal guinea …

MAS Gibson, NS Butters, JN Reynolds… - Neurotoxicology and …, 2000 - Elsevier
Decreased nitric oxide synthase (NOS)–catalyzed formation of NO from l-arginine may be
involved in ethanol teratogenesis involving the hippocampus. This hypothesis was tested by …