Visible‐Light Mediated Tryptophan Modification in Oligopeptides Employing Acylsilanes

J Reimler, A Studer - Chemistry–A European Journal, 2021 - Wiley Online Library
A method for the selective tryptophan modification and labelling of tryptophan‐containing
peptides is described. Photoirradiation of acylsilanes generates reactive siloxycarbenes …

ABNOH‐Linked Nucleotides and DNA for Bioconjugation and Cross‐linking with Tryptophan‐Containing Peptides and Proteins

A Spampinato, DL Leone, R Pohl… - … A European Journal, 2024 - Wiley Online Library
Abstract Reactive N‐hydroxy‐9‐azabicyclo [3.3. 1] nonane (ABNOH) linked 2′‐
deoxyuridine 5′‐O‐mono‐and triphosphates were synthesized through a CuAAC reaction …

Bioconjugation of Au25 Nanocluster to Monoclonal Antibody at Tryptophan

KJ Malawska, S Takano, K Oisaki… - Bioconjugate …, 2023 - ACS Publications
We report the first bioconjugation of Au25 nanocluster to a monoclonal antibody at scarcely
exposed tryptophan (Trp) residues toward the development of high-resolution probes for …

Induction of ADCC by a folic acid–mAb conjugate prepared by tryptophan-selective reaction toward folate-receptor-positive cancer cells

H Tagawa, K Maruyama, K Sasaki, N Konoue… - RSC …, 2020 - pubs.rsc.org
We developed conjugates between monoclonal antibody (mAb) and folic acid (FA) by using
a tryptophan (Trp)-selective reaction, which yields relatively homogenous products …

Catalyst-free site-selective cross-aldol bioconjugations

NDJ Yates, S Akkad, A Noble, T Keenan, NE Hatton… - Green …, 2022 - pubs.rsc.org
The bioconjugation of proteins to small molecules serves as an invaluable tool for probing
biological mechanisms and creating biomaterials. The most powerful bioconjugation …

Electrochemical Tryptophan-Selective Bioconjugation

R Kuroda, E Toyama, T Sugai, M Imai, K Watanabe… - 2025 - chemrxiv.org
Bioconjugation reactions are a fundamental synthetic strategy for generating artificial
peptides and proteins. Although bioconjugates at hydrophobic amino acid residues can offer …

Five-membered ring systems: with more than one N atom

L Yet - Progress in Heterocyclic Chemistry, 2021 - Elsevier
Five-membered ring systems: with more than one N atom - ScienceDirect Skip to main
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Bioconjugation of Electron-Probe Au25 Nanocluster to Monoclonal Antibody

KJ Malawska, S Takano, K Oisaki, H Yanagisawa… - 2022 - chemrxiv.org
We report the first bioconjugation of Au25 nanocluster to a monoclonal antibody without
protein engineering, in a step toward the development of high-resolution probes for …

[CITATION][C] ABNOH-Linked Nucleotides and DNA for Bioconjugation and Cross-linking with Tryptophan-Containing Peptides and Proteins

M Šoltysová, M Polák, A Kádek, V Sýkorová… - Chem. Eur. J, 2024