Copper catalyzed atom transfer radical cyclization reactions

AJ Clark - European Journal of Organic Chemistry, 2016 - Wiley Online Library
Atom transfer radical cyclization (ATRC) is a powerful technique to prepare functionalized 4–
10 membered ring systems using transition metal catalysts. In this review recent advances in …

Copper catalyzed synthesis of seven and higher membered heterocycles

N Kaur - Synthetic Communications, 2019 - Taylor & Francis
Nitrogen, oxygen, and sulfur-containing heterocycles have a wide range of biological
activities. Metal catalysts are used in organic reactions with high activity. New methods have …

Dichloroimidazolidinedione-activated beckmann rearrangement of ketoximes for accessing amides and lactams

Y Gao, J Liu, Z Li, T Guo, S Xu, H Zhu… - The Journal of …, 2018 - ACS Publications
A novel protocol for the activation of the Beckmann rearrangement utilizing the readily
available and economical geminal dichloroimidazolidinediones (DCIDs) on a …

Copper-catalyzed cascade radical addition–cyclization halogen atom transfer between alkynes and unsaturated α-halogenocarbonyls

Y Gao, P Zhang, Z Ji, G Tang, Y Zhao - ACS Catalysis, 2017 - ACS Publications
A Cu-catalyzed cascade radical addition/cyclization/halogen atom transfer between alkynes
and α-halogeno-γ, δ-unsaturated carbonyl compounds for the synthesis of various …

Formation of five-and six-membered heterocyclic rings under radical cyclization conditions

KC Majumdar, GV Karunakar, B Sinha - Synthesis, 2012 - thieme-connect.com
This review describes the formation of five-and six-membered heterocyces in various
organic molecules by radical cyclization and covers the progress made on the topic during …

Stereocontrolled Synthesis of Difunctionalized Azetidinones and β2, 3‐Amino Acid Derivatives from Cyclodienes by Ring‐Opening and Cross‐Metathesis Reactions

M Kardos, L Kiss, F Fülöp - Asian Journal of Organic Chemistry, 2015 - Wiley Online Library
A stereocontrolled approach to highly functionalized 3, 4‐disubstituted azetidin‐2‐ones and
β2, 3‐amino acid derivatives from readily available cycloalkadienes was achieved. The …

β,β,β‐Trichloroethyl‐NH‐Enamine as Viable System for 5‐Endo‐trig Radical Cyclization via Multifaceted CuI−CuII Redox Catalysis: Single Step Synthesis of Multi …

RN Ram, S Sadanandan… - Advanced Synthesis & …, 2019 - Wiley Online Library
Here we report a mild and regioselective copper‐catalyzed direct synthesis of multi‐
substituted and functionalized NH‐pyrroles in high yields from diverse β, β, β‐trichloroethyl …

Recent developments in the synthesis of condensed β-lactams

Y Kumar, P Singh, G Bhargava - RSC advances, 2016 - pubs.rsc.org
β-Lactams are important heterocycles with diverse pharmacological profiles and have
emerged as useful organic synthons. Different variants of β-lactams condensed with carbo …

A decade update on synthesis of bicyclic β-lactams and their transformation into synthetically/biologically relevant carbocyclic and heterocyclic moieties

J Bhalla - Tetrahedron, 2024 - Elsevier
Bicyclic β-lactams constitute an important class of fused-heterocyclic systems which have
remained as an effective fighting tool against wide range of bacterial infections throughout …

Copper(I)/Ligand-Catalyzed 5-endo Radical Cyclization–Aromatization of 2,2,2-Trichloroethyl Vinyl Ethers: Synthesis of 2,3-Difunctionalized 4-Chlorofurans

RN Ram, DK Gupta, VK Soni - The Journal of Organic Chemistry, 2016 - ACS Publications
Copper (I)/ligand-catalyzed one pot synthesis of highly substituted 2, 3-difunctionalized-4-
chlorofurans has been reported. The reaction proceeds via a Cu (I)-catalyzed regioselective …