Constitutive models are important to biomechanics for two key reasons. First, constitutive
modelling is an essential component of characterizing tissues' mechanical properties for …

Head acceleration measurement sensors are now widely deployed in the field to monitor
head kinematic exposure in contact sports. The wealth of impact kinematics data provides …

Rationale: One goal of cardiac tissue engineering is the generation of a living, human pump
in vitro that could replace animal models and eventually serve as an in vivo therapeutic …

Osteoarthritis is a chronic disease that can be initiated by altered joint loading or injury of the
cartilage. The mechanically sensitive PIEZO ion channels have been shown to transduce …

Importance Expensive and lengthy clinical trials can delay regulatory evaluation of
innovative technologies, affecting patient access to high-quality medical products …

Computational fluid dynamics (CFD) is an important tool for the simulation of the
cardiovascular function and dysfunction. Due to the complexity of the anatomy, the …

Acellular epicardial patches that treat myocardial infarction by increasing the mechanical
integrity of damaged left ventricular tissues exhibit widely scattered therapeutic efficacy …

Hyaluronic acid (HA) hydrogels formed via photocrosslinking provide stable 3D hydrogel
environments that support the chondrogenesis of mesenchymal stem cells (MSCs) …

GIBBON, which loosely stands for Geometry and Image-Based Bioengineering add-ON, is a
MATLAB® toolbox providing a single open-source framework for many aspects of …

Understanding how forces orchestrate tissue formation requires technologies to map
internal tissue stress at cellular length scales. Here, we develop ultrasoft mechanosensors …