[HTML][HTML] Olive polyphenols: Antioxidant and anti-inflammatory properties

M Bucciantini, M Leri, P Nardiello, F Casamenti… - Antioxidants, 2021 - mdpi.com
Oxidative stress and inflammation triggered by increased oxidative stress are the cause of
many chronic diseases. The lack of anti-inflammatory drugs without side-effects has …

Nutraceutical properties of olive oil polyphenols. An itinerary from cultured cells through animal models to humans

S Rigacci, M Stefani - International journal of molecular sciences, 2016 - mdpi.com
The increasing interest in the Mediterranean diet hinges on its healthy and anti-ageing
properties. The composition of fatty acids, vitamins and polyphenols in olive oil, a key …

[HTML][HTML] Insights into polyphenol–lipid interactions: Chemical methods, molecular aspects and their effects on membrane structures

M Karonen - Plants, 2022 - mdpi.com
Plant polyphenols have many potential applications, for example, in the fields of chemical
ecology and human and animal health and nutrition. These biological benefits are related to …

Olive polyphenols: New promising agents to combat aging-associated neurodegeneration

F Casamenti, M Stefani - Expert Review of Neurotherapeutics, 2017 - Taylor & Francis
Introduction: Clinical trials and population studies indicate the healthy virtues of the
Mediterranean diet and its main lipid component, extra-virgin olive oil (EVOO). Olive leaves …

Mechanistic understanding from molecular dynamics in pharmaceutical research 2: lipid membrane in drug design

T Róg, M Girych, A Bunker - Pharmaceuticals, 2021 - mdpi.com
We review the use of molecular dynamics (MD) simulation as a drug design tool in the
context of the role that the lipid membrane can play in drug action, ie, the interaction …

Potential role of natural polyphenols against protein aggregation toxicity: in vitro, in vivo, and clinical studies

G Henríquez, A Gomez, E Guerrero… - ACS Chemical …, 2020 - ACS Publications
One of the main features of neurodegenerative disorders such as Alzheimer's disease and
Parkinson's disease is the amyloidogenic behavior of disease-specific proteins including …

[HTML][HTML] Mediterranean Food Industry By-Products as a Novel Source of Phytochemicals with a Promising Role in Cancer Prevention

A Agaj, Ž Peršurić, SK Pavelić - Molecules, 2022 - mdpi.com
The Mediterranean diet is recognized as a sustainable dietary approach with beneficial
health effects. This is highly relevant, although the production of typical Mediterranean food …

In silico pharmacology: Drug membrane partitioning and crossing

F Di Meo, G Fabre, K Berka, T Ossman… - Pharmacological …, 2016 - Elsevier
Over the past decade, molecular dynamics (MD) simulations have become particularly
powerful to rationalize drug insertion and partitioning in lipid bilayers. MD simulations …

Molecular insights into the interactions of theaflavin and epicatechin with different lipid bilayer membranes by molecular dynamics simulation

H Luo, J Chen, L Sun, Z Wang, Z Zhang… - Chemistry and Physics of …, 2024 - Elsevier
At present, consumers increasingly favored the natural food preservatives with fewer side-
effects on health. The green tea catechins and black tea theaflavins attracted considerable …

SARS-CoV-2 Protein S Fusion Peptide Is Capable of Wrap** Negatively-Charged Phospholipids

J Villalaín - Membranes, 2023 - mdpi.com
COVID-19, caused by SARS-CoV-2, which is a positive-sense, single-stranded RNA
enveloped virus, emerged in late 2019 and was declared a worldwide pandemic in early …