Carbohydrate-based macromolecular biomaterials
Carbohydrates are the most abundant and one of the most important biomacromolecules in
Nature. Except for energy-related compounds, carbohydrates can be roughly divided into …
Nature. Except for energy-related compounds, carbohydrates can be roughly divided into …
Smart and bioinspired systems for overcoming biological barriers and enhancing disease theranostics
Nanomedicine has emerged as a promising mean to improve theranostic efficacy and
reduce side effects. Currently, only very small percentage of injected dose reaches the solid …
reduce side effects. Currently, only very small percentage of injected dose reaches the solid …
Targeted and equally distributed delivery of mrna to organs with pentaerythritol-based one-component ionizable amphiphilic janus dendrimers
J Lu, EN Atochina-Vasserman, DS Maurya… - Journal of the …, 2023 - ACS Publications
Delivery of nucleic acids with viral and synthetic vectors has pioneered genetic
nanomedicine. Four-component lipid nanoparticles (LNPs) consisting of ionizable lipids …
nanomedicine. Four-component lipid nanoparticles (LNPs) consisting of ionizable lipids …
Exploring dendrimer-based drug delivery systems and their potential applications in cancer immunotherapy
S Mukherjee, S Mukherjee, MAS Abourehab… - European Polymer …, 2022 - Elsevier
Cancer immunotherapy has been researched as a major modality of treatment which
involves activating the immune system of the patient to fight against tumor cells. Dendrimers …
involves activating the immune system of the patient to fight against tumor cells. Dendrimers …
One-component multifunctional sequence-defined ionizable amphiphilic Janus dendrimer delivery systems for mRNA
D Zhang, EN Atochina-Vasserman… - Journal of the …, 2021 - ACS Publications
Efficient viral or nonviral delivery of nucleic acids is the key step of genetic nanomedicine.
Both viral and synthetic vectors have been successfully employed for genetic delivery with …
Both viral and synthetic vectors have been successfully employed for genetic delivery with …
The unexpected importance of the primary structure of the hydrophobic part of one-component ionizable amphiphilic Janus dendrimers in targeted mRNA delivery …
D Zhang, EN Atochina-Vasserman, J Lu… - Journal of the …, 2022 - ACS Publications
Viral and synthetic vectors for delivery of nucleic acids impacted genetic nanomedicine by
aiding the rapid development of the extraordinarily efficient Covid-19 vaccines. Access to …
aiding the rapid development of the extraordinarily efficient Covid-19 vaccines. Access to …
Engineering functional polymer capsules toward smart nanoreactors
The design and construction of integrated chemical ensembles for studying complex
biological systems is attracting considerable interest in a wide range of research …
biological systems is attracting considerable interest in a wide range of research …
Dendrimer nanosystems for adaptive tumor-assisted drug delivery via extracellular vesicle hijacking
Drug delivery systems (DDSs) that can overcome tumor heterogeneity and achieve deep
tumor penetration are challenging to develop yet in high demand for cancer treatment. We …
tumor penetration are challenging to develop yet in high demand for cancer treatment. We …
Glycopolymer nanobiotechnology
Molecular recognition plays an important role in living systems. 1, 2 Representative
molecular recognitions in living organisms are saccharide− protein, protein− protein, and …
molecular recognitions in living organisms are saccharide− protein, protein− protein, and …
Targeted delivery of mRNA with one-component ionizable amphiphilic Janus dendrimers
D Zhang, EN Atochina-Vasserman… - Journal of the …, 2021 - ACS Publications
Targeted and efficient delivery of nucleic acids with viral and synthetic vectors is the key step
of genetic nanomedicine. The four-component lipid nanoparticle synthetic delivery systems …
of genetic nanomedicine. The four-component lipid nanoparticle synthetic delivery systems …