The understanding of manganese (Mn) biology, in particular its cellular regulation and role
in neurological disease, is an area of expanding interest. Mn is an essential micronutrient …

Manganese (Mn) is an essential heavy metal. However, Mn's nutritional aspects are
paralleled by its role as a neurotoxicant upon excessive exposure. In this review, we …

Neurodegenerative and neuronal-related diseases are major public health concerns.
Human vulnerability to neurodegenerative diseases (NDDs) increases with age. Neuronal …

Manganese (Mn) is the twelfth most abundant element on the earth and an essential metal
to human health. Mn is present at low concentrations in a variety of dietary sources, which …

The develo** brain is extremely sensitive to many chemicals. Perinatal exposure to
neurotoxicants has been implicated in several neurodevelopmental disorders, including …

The essential metal manganese becomes neurotoxic at elevated levels. Yet, the
mechanisms by which brain manganese homeostasis is regulated are unclear. Loss-of …

Ketamine has emerged as a novel strategy to treat refractory depression, producing rapid
remission, but elicits some side effects that limit its use. In an attempt to investigate a safer …

Neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD),
Amyotrophic lateral sclerosis (ALS) and retinal degeneration have been studied extensively …

Current risk assessment guidance calls for an individual chemical‐by‐chemical approach
that fails to capture potential interactive effects of exposure to environmental mixtures and …

Manufacturing of manganese (Mn) compounds, their industrial applications as well as
mining overburden, has generated a potential environmental pollutant. Occupational …