Tocilizumab (actemra)
M Sheppard, F Laskou, PP Stapleton… - Human vaccines & …, 2017 - Taylor & Francis
Tocilizumab (TCZ), is a recombinant humanized anti-interleukin-6 receptor (IL-6R)
monoclonal antibody which has a main use in the treatment of rheumatoid arthritis, systemic …
monoclonal antibody which has a main use in the treatment of rheumatoid arthritis, systemic …
Disease-modifying anti-rheumatic drugs for the management of Takayasu arteritis—a systematic review and meta-analysis
The pharmacotherapy of Takayasu arteritis (TAK) with disease-modifying anti-rheumatic
drugs (DMARDs) is an evolving area. A systematic review of Scopus, Web of Science …
drugs (DMARDs) is an evolving area. A systematic review of Scopus, Web of Science …
2018 Update of the EULAR recommendations for the management of large vessel vasculitis
B Hellmich, A Agueda, S Monti, F Buttgereit… - Annals of the …, 2020 - ard.bmj.com
Background Since the publication of the European League Against Rheumatism (EULAR)
recommendations for the management of large vessel vasculitis (LVV) in 2009, several …
recommendations for the management of large vessel vasculitis (LVV) in 2009, several …
Efficacy and safety of tocilizumab in patients with refractory Takayasu arteritis: results from a randomised, double-blind, placebo-controlled, phase 3 trial in Japan (the …
Y Nakaoka, M Isobe, S Takei, Y Tanaka… - Annals of the …, 2018 - ard.bmj.com
Objective To investigate the efficacy and safety of the interleukin-6 receptor antibody
tocilizumab in patients with Takayasu arteritis (TAK). Methods Patients with TAK who had …
tocilizumab in patients with Takayasu arteritis (TAK). Methods Patients with TAK who had …
Takayasu arteritis
RAG Russo, MM Katsicas - Frontiers in pediatrics, 2018 - frontiersin.org
Takayasu arteritis is an idiopathic granulomatous vasculitis of the aorta and its main
branches and it constitutes one of the more common vasculitides in children. Inflammation …
branches and it constitutes one of the more common vasculitides in children. Inflammation …
Efficacy of biological-targeted treatments in Takayasu arteritis: multicenter, retrospective study of 49 patients
A Mekinian, C Comarmond, M Resche-Rigon… - Circulation, 2015 - Am Heart Assoc
Background—The goal of this work was to assess the safety and efficacy of biologics (ie,
tumor necrosis factor-α antagonists and tocilizumab) in patients with Takayasu arteritis …
tumor necrosis factor-α antagonists and tocilizumab) in patients with Takayasu arteritis …
The effectiveness of tocilizumab and its comparison with tumor necrosis factor alpha inhibitors for takayasu arteritis: a systematic review and meta-analysis
Takayasu arteritis (TAK) refractory to conventional disease-modifying anti-rheumatic drugs
(DMARDs) is commonly treated with biologic DMARDs such as tocilizumab or tumor …
(DMARDs) is commonly treated with biologic DMARDs such as tocilizumab or tumor …
A review of recent advances using tocilizumab in the treatment of rheumatic diseases
A Rubbert-Roth, DE Furst, JM Nebesky, A **… - Rheumatology and …, 2018 - Springer
Tocilizumab (TCZ) is the first humanized anti-interleukin-6 (IL-6) receptor monoclonal
antibody approved for the treatment of patients with rheumatoid arthritis (RA), Castleman's …
antibody approved for the treatment of patients with rheumatoid arthritis (RA), Castleman's …
JCS 2017 guideline on management of vasculitis syndrome―digest version―
Vasculitis is a general term for diseases that cause inflammation in the blood vessels
themselves. Table 1 shows the 2012 revised version of Chapel Hill Consensus Conference …
themselves. Table 1 shows the 2012 revised version of Chapel Hill Consensus Conference …
Tocilizumab mimotope alleviates kidney injury and fibrosis by inhibiting IL-6 signaling and ferroptosis in UUO model
L Yang, J Guo, N Yu, Y Liu, H Song, J Niu, Y Gu - Life Sciences, 2020 - Elsevier
Aims Previously we identified four Tocilizumab mimotopes and antibodies induced by these
mimotopes could bind to IL-6R (interleukin-6 receptor) and regulate the downstream …
mimotopes could bind to IL-6R (interleukin-6 receptor) and regulate the downstream …