TrackMate is an automated tracking software used to analyze bioimages and is distributed
as a Fiji plugin. Here, we introduce a new version of TrackMate. TrackMate 7 is built to …

Extracellular signal-regulated kinase (ERK) has long been studied as a key driver of both
essential cellular processes and disease. A persistent question has been how this single …

Micronuclei are aberrant nuclear compartments that can form as a result of chromosome mis-
segregation. Frequent loss of micronuclear envelope integrity exposes DNA to the …

Synthetic signaling receptors enable programmable cellular responses coupling with
customized inputs. However, engineering a designer force-sensing receptor to rewire …

Tissue repair is a complex process that requires effective communication and coordination
between cells across multiple tissues and organ systems. Two of the initial intracellular …

Recent studies reveal that lateral mitochondrial transfer, the movement of mitochondria from
one cell to another, can affect cellular and tissue homeostasis. Most of what we know about …

Integrin-dependent adhesion to the extracellular matrix (ECM) mediates mechanosensing
and signaling in response to altered microenvironmental conditions. In order to provide …

In response to different cellular stresses, the transcription factor p53 undergoes different
dynamics. p53 dynamics, in turn, control cell fate. However, distinct stresses can generate …

The KRAS oncogene drives many common and highly fatal malignancies. These include
pancreatic, lung, and colorectal cancer, where various activating KRAS mutations have …

Cell-to-cell heterogeneity is vital for tumor evolution and survival. How cancer cells achieve
and exploit this heterogeneity remains an active area of research. Here, we identify c-Myc as …