G protein-coupled receptors in neurodegenerative diseases and psychiatric disorders

TS Wong, G Li, S Li, W Gao, G Chen, S Gan… - … and Targeted Therapy, 2023 - nature.com
Neuropsychiatric disorders are multifactorial disorders with diverse aetiological factors.
Identifying treatment targets is challenging because the diseases are resulting from …

Clinical implications of brain asymmetries

S Ocklenburg, A Mundorf, R Gerrits… - Nature Reviews …, 2024 - nature.com
No two human brains are alike, and with the rise of precision medicine in neurology, we are
seeing an increased emphasis on understanding the individual variability in brain structure …

The genetic architecture of structural left–right asymmetry of the human brain

Z Sha, D Schijven, A Carrion-Castillo, M Joliot… - Nature human …, 2021 - nature.com
Left–right hemispheric asymmetry is an important aspect of healthy brain organization for
many functions including language, and it can be altered in cognitive and psychiatric …

Large-scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium

D Schijven, MC Postema, M Fukunaga… - Proceedings of the …, 2023 - pnas.org
Left–right asymmetry is an important organizing feature of the healthy brain that may be
altered in schizophrenia, but most studies have used relatively small samples and …

The enigma and implications of brain hemispheric asymmetry in neurodegenerative diseases

N Lubben, E Ensink, GA Coetzee… - Brain …, 2021 - academic.oup.com
The lateralization of the human brain may provide clues into the pathogenesis and
progression of neurodegenerative diseases. Though differing in their presentation and …

Brain asymmetries from mid-to late life and hemispheric brain age

M Korbmacher, D van der Meer, D Beck… - Nature …, 2024 - nature.com
The human brain demonstrates structural and functional asymmetries which have
implications for ageing and mental and neurological disease development. We used a set of …

Multi-relation graph convolutional network for Alzheimer's disease diagnosis using structural MRI

J Zhang, X He, L Qing, X Chen, Y Liu… - Knowledge-Based Systems, 2023 - Elsevier
Structural magnetic resonance imaging (sMRI) is widely applied in Alzheimer's disease (AD)
diagnosis tasks by reflecting structural anomalies of the brain. Currently, most existing …

Lateralization of the hippocampus: a review of molecular, functional, and physiological properties in health and disease

SS Nemati, L Sadeghi, G Dehghan… - Behavioural Brain …, 2023 - Elsevier
The hippocampus is a part of the brain's medial temporal lobe that is located under the
cortex. It belongs to the limbic system and helps to collect and transfer information from short …

Regional tau deposition reflects different pathways of subsequent neurodegeneration and memory decline in cognitively normal older adults

X Chen, TN Toueg, TM Harrison, SL Baker… - Annals of …, 2024 - Wiley Online Library
Objective Tau pathology is recognized as a primary contributor to neurodegeneration and
clinical symptoms in Alzheimer's disease (AD). This study aims to localize the early tau …

Diverging asymmetry of intrinsic functional organization in autism

B Wan, SJ Hong, RAI Bethlehem, DL Floris… - Molecular …, 2023 - nature.com
Autism is a neurodevelopmental condition involving atypical sensory-perceptual functions
together with language and socio-cognitive deficits. Previous work has reported subtle …