Understanding the role of the gut microbiome in brain development and its association with neurodevelopmental psychiatric disorders

S Dash, YA Syed, MR Khan - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
The gut microbiome has a tremendous influence on human physiology, including the
nervous system. During fetal development, the initial colonization of the microbiome …

[HTML][HTML] Autism spectrum disorder: Trace elements imbalances and the pathogenesis and severity of autistic symptoms

J Baj, W Flieger, M Flieger, A Forma, E Sitarz… - Neuroscience & …, 2021 - Elsevier
The identification of biomarkers as diagnostic tools and predictors of response to treatment
of neurological developmental disorders (NDD) such as schizophrenia (SZ), attention deficit …

Interaction of heavy metal lead with gut microbiota: implications for autism spectrum disorder

Y Tizabi, S Bennani, N El Kouhen, B Getachew… - Biomolecules, 2023 - mdpi.com
Autism Spectrum Disorder (ASD), a neurodevelopmental disorder characterized by
persistent deficits in social interaction and communication, manifests in early childhood and …

The impact of glutathione metabolism in autism spectrum disorder

G Bjørklund, MD Doşa, M Maes, M Dadar… - Pharmacological …, 2021 - Elsevier
This paper reviews the potential role of glutathione (GSH) in autism spectrum disorder
(ASD). GSH plays a key role in the detoxification of xenobiotics and maintenance of balance …

Targeting microglia in neuroinflammation: H3 receptor antagonists as a novel therapeutic approach for Alzheimer's disease, Parkinson's disease, and autism spectrum …

SD Thomas, S Abdalla, N Eissa, A Akour, NK Jha… - Pharmaceuticals, 2024 - mdpi.com
Histamine performs dual roles as an immune regulator and a neurotransmitter in the
mammalian brain. The histaminergic system plays a vital role in the regulation of …

Repetitive restricted behaviors in autism spectrum disorder: From mechanism to development of therapeutics

J Tian, X Gao, L Yang - Frontiers in neuroscience, 2022 - frontiersin.org
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized
by deficits in social communication, social interaction, and repetitive restricted behaviors …

A role for gene-environment interactions in autism spectrum disorder is supported by variants in genes regulating the effects of exposure to xenobiotics

JX Santos, C Rasga, AR Marques… - Frontiers in …, 2022 - frontiersin.org
Heritability estimates support the contribution of genetics and the environment to the etiology
of Autism Spectrum Disorder (ASD), but a role for gene-environment interactions is …

Pharmacological modulation of HIF-1 in the treatment of neuropsychiatric disorders

D Sharma, H Khan, A Kumar, AK Grewal, K Dua… - Journal of Neural …, 2023 - Springer
Hypoxia-inducible factor 1 has been identified as an important therapeutic target in
psychiatric illnesses. Hypoxia is a condition in which tissues do not receive enough oxygen …

Serum neurofilament light chain and glial fibrillary acidic protein as potential diagnostic biomarkers in autism spectrum disorders: A preliminary study

M Simone, A De Giacomo, R Palumbi… - International Journal of …, 2023 - mdpi.com
Autism spectrum disorder (ASD) is one of the most common neurodevelopment disorders,
characterized by a multifactorial etiology based on the interaction of genetic and …

Ameliorating potential of curcumin and its analogue in central nervous system disorders and related conditions: a review of molecular pathways

P Joshi, A Bisht, S Joshi, D Semwal… - Phytotherapy …, 2022 - Wiley Online Library
Curcumin, isolated from turmeric (Curcuma longa L.) is one of the broadly studied
phytomolecule owing to its strong antioxidant and anti‐inflammatory potential and has been …