There is highly credible evidence that melatonin mitigates cancer at the initiation,
progression and metastasis phases. In many cases, the molecular mechanisms …

Most aspects of mammalian function display circadian rhythms driven by an endogenous
clock. The circadian clock is operated by genes and comprises a central clock in the brain …

Murine studies showed that disruption of circadian clock rhythmicity could lead to cancer
and metabolic syndrome. Time-restricted feeding can reset the disrupted clock rhythm …

Disruption of the circadian rhythm is a contributory factor to clinical and pathophysiological
conditions, including cancer, the metabolic syndrome, and inflammation. Chronic and …

Circadian rhythms are natural rhythms that widely exist in all creatures, and regulate the
processes and physiological functions of various biochemical reactions. The circadian clock …

Metabolic syndrome is characterized by central obesity, insulin resistance, elevated blood
pressure, and dyslipidemia. Metabolic syndrome is a significant risk factor for several …

Introduction: Compelling evidence has highlighted the complex pleiotropic functions elicited
by the melatonin in cancer cells. Melatonin behaves as a 'smart killer', ie, modulating anti …

There is a long history that protracted periods of circadian disruption, such as through
frequent transmeridian travel or rotating shift work, can have a significant impact on brain …

Circadian rhythms are generated via variations in the expression of clock genes that are
organized into a complex transcriptional–translational autoregulatory network and regulate …

Objective The aim of this study was to investigate whether shift work (with or without night
work) is associated with increased risk of breast cancer. Methods The population consisted …