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Binding sites of anticancer drugs on human serum albumin (HSA): a review
Background: To recognize the action of pharmacologically approved anticancer drugs in
biological systems, information regarding its pharmacokinetics, such as its transport within …
biological systems, information regarding its pharmacokinetics, such as its transport within …
Vitamin k3 inhibits protein aggregation: implication in the treatment of amyloid diseases
Protein misfolding and aggregation have been associated with several human diseases
such as Alzheimer's, Parkinson's and familial amyloid polyneuropathy etc. In this study, anti …
such as Alzheimer's, Parkinson's and familial amyloid polyneuropathy etc. In this study, anti …
Spectrofluorimetric and molecular docking studies on the interaction of cyanidin-3-O-glucoside with whey protein, β-lactoglobulin
The interaction of β-Lactoglobulin (β-Lg) with cyanidin-3-O-glucoside (C3G) was
characterized using fluorescence, circular dichroism spectroscopy, and docking studies …
characterized using fluorescence, circular dichroism spectroscopy, and docking studies …
In vitro and in vivo inhibitory effect of anthocyanin-rich bilberry extract on α-glucosidase and α-amylase
Y Ji, D Liu, J Zhao, J Zhao, H Li, L Li, H Zhang, H Wang - Lwt, 2021 - Elsevier
The inhibition of glycosidase activity is regarded as an effective treatment for diabetes
mellitus. Bilberry (Vaccinium myrtillus L.) fruit has a high content of anthocyanins with …
mellitus. Bilberry (Vaccinium myrtillus L.) fruit has a high content of anthocyanins with …
Investigation of inhibitory potential of quercetin to the pyruvate dehydrogenase kinase 3: Towards implications in anticancer therapy
Abstract Pyruvate dehydrogenase kinase 3 (PDK3) is a mitochondrial protein, has recently
been considered as a potential pharmacological target for varying types of cancer. Here, we …
been considered as a potential pharmacological target for varying types of cancer. Here, we …
Ascorbic acid inhibits human insulin aggregation and protects against amyloid induced cytotoxicity
Protein aggregation into oligomers and fibrils are associated with many human
pathophysiologies. Compounds that modulate protein aggregation and interact with …
pathophysiologies. Compounds that modulate protein aggregation and interact with …
Investigating the site selective binding of busulfan to human serum albumin: Biophysical and molecular docking approaches
We have studied the binding of busulfan (BN) to human serum albumin (HSA) at
physiological pH 7.4 by using fluorescence, UV–vis and circular dichroism (CD) …
physiological pH 7.4 by using fluorescence, UV–vis and circular dichroism (CD) …
Investigation of the interaction between Chrysoeriol and xanthine oxidase using computational and in vitro approaches
Y Liu, C Han, T Lu, Y Liu, H Chen, C Yang, Y Tu… - International Journal of …, 2021 - Elsevier
Xanthine oxidase (XO) plays a vital role in inducing hyperuricemia and increasing the level
of superoxide free radicals in blood, and is proved as an important target for gout …
of superoxide free radicals in blood, and is proved as an important target for gout …
Discovery of 8-hydroxy-2-quinoline carbaldehyde derivatives as inhibitors for M1 aminopeptidase of leishmania donovani
M1 aminopeptidase is a metallopeptidase that plays a vital role in protein catabolism and
has been identified as a validated drug target in various parasites; however, our …
has been identified as a validated drug target in various parasites; however, our …
Anti-amyloidogenic behavior and interaction of diallylsulfide with human serum albumin
In this work, binding of garlic component-Diallysulfide (DAS) with major human blood
transport protein, Human Serum Albumin (HSA) and its anti-amyloidogenic behavior has …
transport protein, Human Serum Albumin (HSA) and its anti-amyloidogenic behavior has …