Photoactive ruthenium nitrosyls: Effects of light and potential application as NO donors
MJ Rose, PK Mascharak - Coordination chemistry reviews, 2008 - Elsevier
In recent years, various exogenous nitric oxide (NO) donors have been synthesized to
modulate NO concentrations in cellular environments and control physiological processes …
modulate NO concentrations in cellular environments and control physiological processes …
Biological activity of ruthenium nitrosyl complexes
Nitric oxide plays an important role in various biological processes, such as
neurotransmission, blood pressure control, immunological responses, and antioxidant …
neurotransmission, blood pressure control, immunological responses, and antioxidant …
In vitro and in vivo antiproliferative and trypanocidal activities of ruthenium NO donors
JJN Silva, AL Osakabe, WR Pavanelli… - British journal of …, 2007 - Wiley Online Library
Background and purpose: Many compounds liberating NO (NO donors) have been used as
therapeutic agents. Here we test two ruthenium nitrosyls, which release NO when activated …
therapeutic agents. Here we test two ruthenium nitrosyls, which release NO when activated …
Tailoring NO donors metallopharmaceuticals: ruthenium nitrosyl ammines and aliphatic tetraazamacrocycles
E Tfouni, FG Doro, LE Figueiredo… - Current medicinal …, 2010 - ingentaconnect.com
The discovery of the involvement of nitric oxide (NO) in several physiological and
pathophysiological processes launched a spectacular increase in studies in areas such as …
pathophysiological processes launched a spectacular increase in studies in areas such as …
Ru (II) and Ru (III) complexes with cyclam and related species
The properties of cyclam, cyclen, and 1-(3-propylammonium) complexes of ruthenium
(II/III),[Ru (macrocycle) LL′] n+, and related species are reviewed. L and L′ are ligands …
(II/III),[Ru (macrocycle) LL′] n+, and related species are reviewed. L and L′ are ligands …
Photochemical reactions of trans-[Ru (NH3) 4L (NO)] 3+ complexes
RM Carlos, AA Ferro, HAS Silva, MG Gomes… - Inorganica chimica …, 2004 - Elsevier
The photochemical behavior of a series of trans-[Ru (NH3) 4L (NO)] 3+ complexes, where
L= nitrogen bound imidazole, L-histidine, 4-picoline, pyridine, nicotinamide, pyrazine, 4 …
L= nitrogen bound imidazole, L-histidine, 4-picoline, pyridine, nicotinamide, pyrazine, 4 …
Apocynin reduces blood pressure and restores the proper function of vascular endothelium in SHR
This study has evaluated how the vascular endothelium of hypertensive rats chronically
treated with apocynin affects acetylcholine (ACh), sodium nitroprusside (SNP), and …
treated with apocynin affects acetylcholine (ACh), sodium nitroprusside (SNP), and …
[HTML][HTML] Nitric oxide synthesis and biological functions of nitric oxide released from ruthenium compounds
During three decades, an enormous number of studies have demonstrated the critical role of
nitric oxide (NO) as a second messenger engaged in the activation of many systems …
nitric oxide (NO) as a second messenger engaged in the activation of many systems …
A macrocyclic nitrosyl ruthenium complex is a NO donor that induces rat aorta relaxation
D Bonaventura, FS Oliveira, V Togniolo, AC Tedesco… - Nitric oxide, 2004 - Elsevier
The vasorelaxation induced by a nitrosyl macrocyclic ruthenium complex, proposed as a
new nitric oxide (NO) carrier, was studied in rat isolated aorta. The compound trans-[RuCl …
new nitric oxide (NO) carrier, was studied in rat isolated aorta. The compound trans-[RuCl …
[HTML][HTML] Hypotensive and vasorelaxing effects of the new NO-donor [Ru (terpy)(bdq) NO+] 3+ in spontaneously hypertensive rats
Drugs that release nitric oxide (NO) usually have limitations due to their harmful effects.
Sodium nitroprusside (SNP) induces a rapid hypotension that leads to reflex tachycardia …
Sodium nitroprusside (SNP) induces a rapid hypotension that leads to reflex tachycardia …