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Therapeutic advances in multiple sclerosis
Multiple sclerosis (MS) is an autoimmune disease affecting the central nervous system that
causes significant disability and healthcare burden. The treatment of MS has evolved over …
causes significant disability and healthcare burden. The treatment of MS has evolved over …
Immunological aspects of approved MS therapeutics
Multiple sclerosis (MS) is the most common neurological immune-mediated disease leading
to disability in young adults. The outcome of the disease is unpredictable, and over time …
to disability in young adults. The outcome of the disease is unpredictable, and over time …
ECTRIMS/EAN guideline on the pharmacological treatment of people with multiple sclerosis
Background: Multiple sclerosis (MS) is a complex disease with new drugs becoming
available in the past years. There is a need for a reference tool compiling current data to aid …
available in the past years. There is a need for a reference tool compiling current data to aid …
Silent progression in disease activity–free relapsing multiple sclerosis
University of California, San Francisco MS … - Annals of …, 2019 - Wiley Online Library
Objective Rates of worsening and evolution to secondary progressive multiple sclerosis
(MS) may be substantially lower in actively treated patients compared to natural history …
(MS) may be substantially lower in actively treated patients compared to natural history …
Teriflunomide and time to clinical multiple sclerosis in patients with radiologically isolated syndrome: the TERIS randomized clinical trial
Importance Radiologically isolated syndrome (RIS) represents the earliest detectable
preclinical phase of multiple sclerosis (MS) punctuated by incidental magnetic resonance …
preclinical phase of multiple sclerosis (MS) punctuated by incidental magnetic resonance …
The disease-modifying therapies of relapsing-remitting multiple sclerosis and liver injury: a narrative review
In this narrative review, we analyze pre-registration and post-marketing data concerning
hepatotoxicity of all disease-modifying therapies (DMTs) available for the treatment of …
hepatotoxicity of all disease-modifying therapies (DMTs) available for the treatment of …
Early use of high-efficacy therapies in multiple sclerosis in the United States: benefits, barriers, and strategies for encouraging adoption
BA Singer, J Feng, H Chiong-Rivero - Journal of Neurology, 2024 - Springer
Multiple sclerosis (MS) is characterized by progressive neuroinflammation and
neurodegeneration from disease onset that, if left untreated, can result in the accumulation …
neurodegeneration from disease onset that, if left untreated, can result in the accumulation …
Safety and efficacy of teriflunomide in paediatric multiple sclerosis (TERIKIDS): a multicentre, double-blind, phase 3, randomised, placebo-controlled trial
Background Therapeutic options for children with multiple sclerosis are scarce.
Teriflunomide is approved in more than 80 countries for the treatment of adults with …
Teriflunomide is approved in more than 80 countries for the treatment of adults with …
Infections in patients receiving multiple sclerosis disease-modifying therapies
E Grebenciucova, A Pruitt - Current neurology and neuroscience reports, 2017 - Springer
Abstract Purpose of Review This paper will systemically review the risk of infections
associated with current disease-modifying treatments and will discuss pre-treatment testing …
associated with current disease-modifying treatments and will discuss pre-treatment testing …
Efficacy and safety of the newer multiple sclerosis drugs approved since 2010
S Faissner, R Gold - CNS drugs, 2018 - Springer
Multiple sclerosis treatment faces tremendous changes as a result of the approval of new
medications. The new medications have differing safety considerations and risks after long …
medications. The new medications have differing safety considerations and risks after long …