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Astrocytes in human central nervous system diseases: a frontier for new therapies
Astroglia are a broad class of neural parenchymal cells primarily dedicated to homoeostasis
and defence of the central nervous system (CNS). Astroglia contribute to the …
and defence of the central nervous system (CNS). Astroglia contribute to the …
[HTML][HTML] Beyond the GFAP-astrocyte protein markers in the brain
AM Jurga, M Paleczna, J Kadluczka, KZ Kuter - Biomolecules, 2021 - mdpi.com
The idea of central nervous system as one-man band favoring neurons is long gone. Now
we all are aware that neurons and neuroglia are team players and constant communication …
we all are aware that neurons and neuroglia are team players and constant communication …
Microglia-astrocyte crosstalk: an intimate molecular conversation
Microglia-astrocyte crosstalk has recently been at the forefront of glial research. Emerging
evidence illustrates that microglia-and astrocyte-derived signals are the functional …
evidence illustrates that microglia-and astrocyte-derived signals are the functional …
Glial responses to implanted electrodes in the brain
The use of implants that can electrically stimulate or record electrophysiological or
neurochemical activity in nervous tissue is rapidly expanding. Despite remarkable results in …
neurochemical activity in nervous tissue is rapidly expanding. Despite remarkable results in …
Astrocytes: a central element in neurological diseases
The neurone-centred view of the past disregarded or downplayed the role of astroglia as a
primary component in the pathogenesis of neurological diseases. As this concept is …
primary component in the pathogenesis of neurological diseases. As this concept is …
Astrocyte metabolism and signaling pathways in the CNS
Y Zhang, Y Qi, Y Gao, W Chen, T Zhou… - Frontiers in …, 2023 - frontiersin.org
Astrocytes comprise half of the cells in the central nervous system and play a critical role in
maintaining metabolic homeostasis. Metabolic dysfunction in astrocytes has been indicated …
maintaining metabolic homeostasis. Metabolic dysfunction in astrocytes has been indicated …
Decoupling astrocytes in adult mice impairs synaptic plasticity and spatial learning
L Hösli, N Binini, KD Ferrari, L Thieren, ZJ Looser… - Cell reports, 2022 - cell.com
The mechanisms by which astrocytes modulate neural homeostasis, synaptic plasticity, and
memory are still poorly explored. Astrocytes form large intercellular networks by gap junction …
memory are still poorly explored. Astrocytes form large intercellular networks by gap junction …
[HTML][HTML] Direct vascular contact is a hallmark of cerebral astrocytes
L Hösli, M Zuend, G Bredell, HS Zanker… - Cell reports, 2022 - cell.com
Astrocytes establish extensive networks via gap junctions that allow each astrocyte to
connect indirectly to the vasculature. However, the proportion of astrocytes directly …
connect indirectly to the vasculature. However, the proportion of astrocytes directly …
The role of astrocyte‐mediated plasticity in neural circuit development and function
Neuronal networks are capable of undergoing rapid structural and functional changes called
plasticity, which are essential for sha** circuit function during nervous system …
plasticity, which are essential for sha** circuit function during nervous system …
[HTML][HTML] Astrocyte-neuron circuits in epilepsy
The epilepsies are a diverse spectrum of disease states characterized by spontaneous
seizures and associated comorbidities. Neuron-focused perspectives have yielded an array …
seizures and associated comorbidities. Neuron-focused perspectives have yielded an array …