Although the first ancient DNA molecules were extracted more than three decades ago, the
first ancient nuclear genomes could only be characterized after high-throughput sequencing …

Transposable elements (TEs) are genetic elements with the ability to mobilize and replicate
themselves in a genome. Mammalian genomes are dominated by TEs, which can reach …

During the last glacial–interglacial cycle, Arctic biotas experienced substantial climatic
changes, yet the nature, extent and rate of their responses are not fully understood …

Although an inverse relationship is expected in ancient DNA samples between the number
of surviving DNA fragments and their length, ancient DNA sequencing libraries are strikingly …

Neandertals, the closest evolutionary relatives of present-day humans, lived in large parts of
Europe and western Asia before disappearing 30,000 years ago. We present a draft …

Next-generation sequencing technologies have revolutionized the field of paleogenomics,
allowing the reconstruction of complete ancient genomes and their comparison with modern …

Genome sequencing projects were long confined to biomedical model organisms and
required the concerted effort of large consortia. Rapid progress in high‐throughput …

This protocol describes a method for converting short single-stranded and double-stranded
DNA into libraries compatible with high-throughput sequencing using Illumina technology …

As most biologists are probably aware, technological advances in molecular biology during
the last few years have opened up possibilities to rapidly generate large-scale sequencing …

Phytophthora infestans, the cause of potato late blight, is infamous for having triggered the
Irish Great Famine in the 1840s. Until the late 1970s, P. infestans diversity outside of its …