Importance Schizophrenia is a common, severe mental illness that most clinicians will
encounter regularly during their practice. This report provides an overview of the clinical …

This review considers computational psychiatry from a particular viewpoint: namely, a
commitment to explaining psychopathology in terms of pathophysiology. It rests on the …

Glutamate and dopamine systems play distinct roles in terms of neuronal signalling, yet both
have been proposed to contribute significantly to the pathophysiology of schizophrenia. In …

Rhythms are a fundamental and defining feature of neuronal activity in animals including
humans. This rhythmic brain activity interacts in complex ways with rhythms in the internal …

Economics and mental health are intertwined. Apart from the accumulating evidence of the
huge economic impacts of mental ill‐health, and the growing recognition of the effects that …

Imaging human brain function with techniques such as magnetoencephalography typically
requires a subject to perform tasks while their head remains still within a restrictive scanner …

Working memory is the fundamental function by which we break free from reflexive input-
output reactions to gain control over our own thoughts. It has two types of mechanisms …

Structural and transcriptional changes during early brain maturation follow fixed
developmental programs defined by genetics. However, whether this is true for functional …

Schizophrenia is a debilitating mental illness which involves three groups of symptoms, ie,
positive, negative and cognitive, and has major public health implications. According to …

Our incomplete understanding of the link between Alzheimer's Disease pathology and
symptomatology is a crucial obstacle for therapeutic success. Recently, translational studies …