Nanoparticle drug delivery systems and their applications as targeted therapies for triple negative breast cancer

X Kong, Y Qi, X Wang, R Jiang, J Wang, Y Fang… - Progress in Materials …, 2023 - Elsevier
The therapeutic effect of highly malignant triple negative breast cancer (TNBC) is negatively
affected by the formation of tumor cell resistant clone and the severe toxicity of …

Triple-negative breast cancer: a review of conventional and advanced therapeutic strategies

MA Medina, G Oza, A Sharma, LG Arriaga… - International journal of …, 2020 - mdpi.com
Triple-negative breast cancer (TNBC) cells are deficient in estrogen, progesterone and
ERBB2 receptor expression, presenting a particularly challenging therapeutic target due to …

Triple-negative breast cancer: a brief review about epidemiology, risk factors, signaling pathways, treatment and role of artificial intelligence

NM Almansour - Frontiers in Molecular Biosciences, 2022 - frontiersin.org
Triple-negative breast cancer (TNBC) is a kind of breast cancer that lacks estrogen,
progesterone, and human epidermal growth factor receptor 2. This cancer is responsible for …

Nanoparticle-based drug delivery systems in cancer: A focus on inflammatory pathways

AR Afshari, M Sanati, H Mollazadeh… - Seminars in cancer …, 2022 - Elsevier
It has become necessary to accept the clinical reality of therapeutic agents targeting the
cancer-associated immune system. In recent decades, several investigations have …

Advanced functional nanomaterials for theranostics

H Huang, JF Lovell - Advanced functional materials, 2017 - Wiley Online Library
Nanoscale materials have been explored extensively as agents for therapeutic and
diagnostic (ie, theranostic) applications. Research efforts have shifted from exploring new …

Versatile types of polysaccharide-based drug delivery systems: From strategic design to cancer therapy

Y Sun, X **g, X Ma, Y Feng, H Hu - International Journal of Molecular …, 2020 - mdpi.com
Chemotherapy is still the most direct and effective means of cancer therapy nowadays. The
proposal of drug delivery systems (DDSs) has effectively improved many shortcomings of …

Functionalized superparamagnetic iron oxide nanoparticles (SPIONs) as platform for the targeted multimodal tumor therapy

C Janko, T Ratschker, K Nguyen, L Zschiesche… - Frontiers in …, 2019 - frontiersin.org
Standard cancer treatments involve surgery, radiotherapy, chemotherapy, and
immunotherapy. In clinical practice, the respective drugs are applied orally or intravenously …

[HTML][HTML] Nanosoldiers: A promising strategy to combat triple negative breast cancer

A Pawar, P Prabhu - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Abstracts The phenomenal rise in cancer over the past few years has made it the second
leading cause of death worldwide. Breast cancer constitutes the predominant cancer …

SPIONs conjugate supported anticancer drug doxorubicin's delivery: current status, challenges, and prospects

N Akhtar, HA Mohammed, M Yusuf, A Al-Subaiyel… - Nanomaterials, 2022 - mdpi.com
Considerable efforts have been directed towards development of nano-structured carriers to
overcome the limitations of anticancer drug, doxorubicin's, delivery to various cancer sites …

Polysaccharides based nanomaterials for targeted anti-cancer drug delivery

D Dheer, D Arora, S Jaglan, RK Rawal… - Journal of drug …, 2017 - Taylor & Francis
Polysaccharides, an important class of biological polymers, are effectively bioactive,
nontoxic, hydrophilic, biodegradable and offer a wide diversity in structure and properties …