Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death
globally and liver transplantation (LT) can serve as the best curative treatment option …

CD8+ Tregs have been long described and significant progresses have been made about
their phenotype, their functional mechanisms, and their suppressive ability compared to …

Bronchiolitis obliterans syndrome (BOS) is a major impediment to lung transplant survival
and is generally resistant to medical therapy. Extracorporeal photophoresis (ECP) is an …

Allograft failure remains a major barrier in the field of lung transplantation and results
primarily from acute and chronic rejection. To date, standard-of-care immunosuppressive …

Although cluster of differentiation (CD) 8+ regulatory T (Treg) cells have been in the last 20
years more studied since evidences of their role in tolerance as been demonstrated in …

Immune checkpoint (IC) molecules modulate immune responses upon antigen presentation;
the interaction between different IC molecules will result in the stimulation or, rather, the …

Obliterative bronchiolitis (OB) is a poorly understood airway disease characterized by the
generation of fibrotic bronchiolar occlusions. In the lung transplant setting, OB is a …

Pathways regulating lung alloimmune responses differ from most other solid organs and
remain poorly explored. Based on our recent work identifying the unique role of eosinophils …

Despite the accepted notion that granulocytes play a universally destructive role in organ
and tissue grafts, it has been recently described that eosinophils can facilitate …

The promising outcomes of immune‐checkpoint based immunotherapies in cancer have
provided a proportional perspective ahead of exploiting similar approaches in …