Dual-functional hydroxyapatite scaffolds for bone regeneration and precision drug delivery

A Farazin, S Mahjoubi - Journal of the Mechanical Behavior of Biomedical …, 2024 - Elsevier
Addressing infected bone defects remains a significant challenge in orthopedics, requiring
effective infection control and bone defect repair. A promising therapeutic approach involves …

Nanostructured polymer composites for bone and tissue regeneration

EV Prathyusha, SS Gomte, H Ahmed… - International Journal of …, 2024 - Elsevier
Nanostructured polymer composites have gained significant attention in recent years for
their remarkable potential in bone and tissue regeneration. Moreover, with the integration of …

Development of polyvinyl alcohol nanofiber scaffolds loaded with flaxseed extract for bone regeneration: phytochemicals, cell proliferation, adhesion, and osteogenic …

AG Abdelaziz, H Nageh, MS Abdalla, SM Abdo… - Frontiers in …, 2024 - frontiersin.org
Introduction: Bone tissue engineering seeks innovative materials that support cell growth
and regeneration. Electrospun nanofibers, with their high surface area and tunable …

[HTML][HTML] Enhancing 3D Scaffold Performance for Bone Tissue Engineering: A Comprehensive Review of Modification and Functionalization Strategies

M Selim, HM Mousa, GT Abdel-Jaber… - Journal of Science …, 2024 - Elsevier
Bone tissue engineering holds promise for addressing bone injuries by using biomaterial-
based 3D scaffolds. The efficacy of these scaffolds is paramount, relying heavily on their …

[HTML][HTML] Mechanical and fatigue performance of multidirectional functionally graded Ti6Al4V scaffolds produced via laser powder bed fusion for orthopedic implants

R Gandhi, M Salmi, B Roy, L Pauli, L Pagliari, F Concli - Materials & Design, 2025 - Elsevier
Orthopedic implants require porosity gradients to achieve tissue integration and mechanical
support. This study presents a novel design of Multidirectional Functionally Graded (MDFG) …

Chitosan microporous foam filled 3D printed polylactic acid-pearl macroporous scaffold: Dual-scale porous structure, biological and mechanical properties

W Guo, Z Peng, D Ning, Y Wu, Y Mao, E Wang… - International Journal of …, 2025 - Elsevier
A bone scaffold with well-designed porous structure and material composition is essential
for bone regeneration as it supports various biological functions. In this study, a dual-scale …

Unveiling the potential of pullulan in enhancing ketoprofen release from PHBV filaments

LT de Carvalho, MB da Silva, TA Vieira, LS Maia… - International Journal of …, 2025 - Elsevier
In this study, sustainable poly (3-hydroxybutyrate-co-3-hydroxyvalerate)(PHBV) and pullulan
(PUL)/PHBV filaments were prepared with ketoprofen for scaffold preparation. The research …

[HTML][HTML] Bioinspired PCL-Based Composite Scaffolds Produced via Hot Melt Extrusion and Fused Filament Fabrication: An Integrated Workflow for Enhanced Bone …

C Tommasino, C Sardo, A Guidone, A Soriente… - Journal of Drug Delivery …, 2025 - Elsevier
This study presents a comprehensive and integrated workflow for fabricating bioinspired,
macroporous 3D scaffolds tailored for bone tissue engineering. Poly-(ε-caprolactone)(PCL) …

Technique of 3D printing for scaffolding in tissue engineering of bones: Opportunities and challenges

R Jaiswal, R Wadetwar - Materials Today Communications, 2025 - Elsevier
The technique of 3D printing is emerging. To fulfill the demands of various patients, it can
swiftly and precisely produce scaffolds for bone tissue engineering using customized forms …

[HTML][HTML] Mechanical Properties and Decomposition Behavior of Compression Moldable Poly(Malic Acid)/α-Tricalcium Phosphate Hybrid Materials

S Hara, A Kojima, A Furukawa, T Toyama, H Ikake… - Polymers, 2025 - mdpi.com
Calcified tissues in living organisms, such as bone, dentin, and enamel, often require
surgical intervention for treatment. However, advances in regenerative medicine have …