Multiple roles for orexin/hypocretin in addiction

SV Mahler, RJ Smith, DE Moorman, GC Sartor… - Progress in brain …, 2012 - Elsevier
Orexins/hypocretins are hypothalamic peptides involved in arousal and wakefulness, but
also play a critical role in drug addiction and reward-related behaviors. Here, we review the …

Hypersomnia and depressive symptoms: methodological and clinical aspects

Y Dauvilliers, R Lopez, M Ohayon, S Bayard - BMC medicine, 2013 - Springer
The associations between depressive symptoms and hypersomnia are complex and often
bidirectional. Of the many disorders associated with excessive sleepiness in the general …

Narcolepsy is complicated by high medical and psychiatric comorbidities: a comparison with the general population

MM Ohayon - Sleep medicine, 2013 - Elsevier
BACKGROUND: Individuals affected with narcolepsy represent a vulnerable segment of the
population. However, we only have a partial understanding of this vulnerability. Our study …

Listening to the patient voice in narcolepsy: diagnostic delay, disease burden, and treatment efficacy

K Maski, E Steinhart, D Williams… - Journal of Clinical …, 2017 - jcsm.aasm.org
Study Objectives: Describe common symptoms, comorbidities, functional limitations, and
treatment responsiveness among patients with narcolepsy. Investigate the effect of pediatric …

Hypersomnolence, hypersomnia, and mood disorders

L Barateau, R Lopez, JAM Franchi… - Current psychiatry reports, 2017 - Springer
Relationships between symptoms of hypersomnolence, psychiatric disorders, and
hypersomnia disorders (ie, narcolepsy and idiopathic hypersomnia) are complex and …

Treatment options for narcolepsy

L Barateau, R Lopez, Y Dauvilliers - CNS drugs, 2016 - Springer
Narcolepsy type 1 and narcolepsy type 2 are central disorders of hypersomnolence.
Narcolepsy type 1 is characterized by excessive daytime sleepiness and cataplexy and is …

The clinical spectrum of childhood narcolepsy

E Postiglione, E Antelmi, F Pizza, M Lecendreux… - Sleep Medicine …, 2018 - Elsevier
Narcolepsy type 1 is a life-long, severe, multifaceted disease often arising in childhood or
adolescence. Beyond the classical symptoms (excessive daytime sleepiness, cataplexy …

Search for third generation scalar leptoquarks in pp collisions at TeV with the ATLAS detector

G Aad, T Abajyan, B Abbott, J Abdallah… - Journal of High Energy …, 2013 - Springer
A bstract A search for pair-produced third generation scalar leptoquarks is presented, using
proton-proton collisions at\(\sqrt {s}= 7\) TeV at the LHC. The data were recorded with the …

[PDF][PDF] Narcolepsy: Diagnosis and management

EC Golden, MC Lipford - Cleve Clin J Med, 2018 - cdn.mdedge.com
Narcolepsy is a chronic disorder of hypersomnia that can have a significant impact on
quality of life and livelihood. However, with appropriate treatment, its symptoms are …

The humanistic and economic burden of narcolepsy

NM Flores, KF Villa, J Black, RD Chervin… - Journal of Clinical Sleep …, 2016 - jcsm.aasm.org
Study Objectives: To evaluate the burden of narcolepsy--with respect to psychiatric
comorbidities, Health-Related Quality of Life (HRQoL), direct costs for healthcare resource …