Protein complexes are one of the most important functional units for deriving biological
processes within the cell. Experimental methods have provided valuable data to infer protein …

Viral infection involves a large number of protein–protein interactions (PPIs) between human
and virus. The PPIs range from the initial binding of viral coat proteins to host membrane …

Protein-protein interactions (PPIs) are the physical connections between two or more
proteins via electrostatic forces or hydrophobic effects. Identification of the PPIs is pivotal …

Motivation Biological experimental approaches to protein–protein interaction (PPI) site
prediction are critical for understanding the mechanisms of biochemical processes but are …

Identifying the informative genes has always been a major step in microarray data analysis.
The complexity of various cancer datasets makes this issue still challenging. In this paper, a …

Background Proteins perform their functions usually by interacting with other proteins.
Predicting which proteins interact is a fundamental problem. Experimental methods are …

Protein-protein interactions exist ubiquitously and play important roles in the life cycles of
living cells. The interaction sites (residues) are essential to understanding the underlying …

The large-scale identification of protein–protein interactions (PPIs) between humans and
bacteria remains a crucial step in systematically understanding the underlying molecular …

Position-specific scoring matrix (PSSM), also called profile, is broadly used for representing
the evolutionary history of a given protein sequence. Several investigations reported that the …

Proteins and their interactions play a key role in the realization of all cellular biological
activities of organisms. Therefore, prediction of protein-protein interactions is crucial for …