Uric acid and cardiovascular risk

DI Feig, DH Kang, RJ Johnson - New England journal of …, 2008 - Mass Medical Soc
This review summarizes relevant studies concerning uric acid and possible links to
hypertension, renal disease, and cardiovascular disease. Whether uric acid is an …

[HTML][HTML] Uric acid and cardiovascular disease: a clinical review

Y Saito, A Tanaka, K Node, Y Kobayashi - Journal of cardiology, 2021 - Elsevier
Uric acid, the end-product of purine metabolism in humans, is not only a cause of gout, but
also may play roles in develo** cardiovascular diseases such as hypertension, atrial …

Uric acid and cardiovascular disease

G Ndrepepa - Clinica chimica acta, 2018 - Elsevier
Uric acid (UA) is an end product of purine metabolism in humans and great apes. UA acts as
an antioxidant and it accounts for 50% of the total antioxidant capacity of biological fluids in …

Identification of the uric acid thresholds predicting an increased total and cardiovascular mortality over 20 years

A Virdis, S Masi, E Casiglia, V Tikhonoff, AFG Cicero… - …, 2020 - Am Heart Assoc
Serum uric acid (SUA) levels discriminating across the different strata of cardiovascular risk
is still unknown. By utilizing a large population-based database, we assessed the threshold …

Uric acid is a risk factor for myocardial infarction and stroke: the Rotterdam study

MJ Bos, PJ Koudstaal, A Hofman, JCM Witteman… - Stroke, 2006 - Am Heart Assoc
Background and Purpose—The role of uric acid as a risk factor for myocardial infarction is
controversial, and little is known about its role as a risk factor for stroke. Recent evidence …

Uric acid and inflammatory markers

C Ruggiero, A Cherubini, A Ble, AJG Bos… - European heart …, 2006 - academic.oup.com
Aims The role of uric acid (UA) in the process of atherosclerosis and atherotrombosis is
controversial. Epidemiological studies have recently shown that UA may be a risk factor for …

Independent impact of gout on mortality and risk for coronary heart disease

HK Choi, G Curhan - Circulation, 2007 - Am Heart Assoc
Background—Although gout and hyperuricemia are related to several conditions that are
associated with reduced survival, no prospective data are available on the independent …

[HTML][HTML] Uric acid, hyperuricemia and vascular diseases

M **, F Yang, I Yang, Y Yin, JJ Luo… - … in bioscience: a …, 2012 - ncbi.nlm.nih.gov
Uric acid is the product of purine metabolism. It is known that hyperuricemia, defined as high
levels of blood uric acid, is the major etiological factor of gout. A number of epidemiological …

Uric acid: A new look at an old risk marker for cardiovascular disease, metabolic syndrome, and type 2 diabetes mellitus: The urate redox shuttle

MR Hayden, SC Tyagi - Nutrition & metabolism, 2004 - Springer
Background The topical role of uric acid and its relation to cardiovascular disease, renal
disease, and hypertension is rapidly evolving. Its important role both historically and …

Empagliflozin as add-on to metformin plus sulfonylurea in patients with type 2 diabetes: a 24-week, randomized, double-blind, placebo-controlled trial

HU Häring, L Merker, E Seewaldt-Becker… - Diabetes …, 2013 - Am Diabetes Assoc
OBJECTIVE To investigate the efficacy and tolerability of empagliflozin as add-on to
metformin and sulfonylurea in patients with type 2 diabetes. RESEARCH DESIGN AND …